You asked about IoT
218 people built something like it. 27 are gone.
That is 14% of the ones whose fate we could settle, against 23% across the whole register. 25 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2012-06-01 | Unlocking the power of biotech with modern software for modern science · benchling.com | still up |
| 2021-01-01 | YCTractian Physical AI for asset-heavy industries · tractian.com | still up |
| 2015-01-01 | YCChariot The world's first private mass transit service providing a commuting… · chariot.com | acquired |
| 2016-01-01 | We make robots for biologists. · opentrons.com | still up |
| 2016-06-01 | YCgarten Creating workplace wellbeing. · garten.co | acquired |
| 2017-01-01 | YCSolugen Decarbonizing the chemicals industry. · solugen.com | still up |
| 2020-01-01 | YCRiot Cybersecurity awareness for fast growing companies · tryriot.com | still up |
| 2017-01-01 | YCUpKeep Mobile-first software for maintenance teams. · upkeep.com | acquired |
| 2022-06-15 | exaluminal.com | still up |
| 2016-06-01 | YCValidere A carbon MRV solution for energy and hard-to-abate sectors · validere.com | still up |
| 2022-02-10 | kraftful.com | still up |
| 2021-01-01 | YCgaiia all-in-one operating system (OS) for telcos · gaiia.com | still up |
| 2012-01-01 | YCRidecell World's Leading Fleet Intelligence Platform · ridecell.com | still up |
| 2019-01-01 | YCMemfault First IoT reliability platform for debugging, monitoring, OTA updates · memfault.com | acquired |
| 2020-01-01 | Next-generation DNA synthesis using enzymes · ansabio.com | still up |
| 2015-01-01 | Artificial intelligence for drug discovery. · numerionlabs.ai | still up |
| 2022-01-01 | Plug-and-play AI platform with sensors and dashboards that makes… · iotflows.com | still up |
| 2016-01-01 | YCLygos Lygos engineers yeast to convert sugar into high-value industrial… · lygos.com | still up |
| 2020-01-01 | Foundation models and autonomous chambers for plant biology · urbankisaan.com | still up |
| 2015-01-01 | Bluesmart makes smart luggage powered by an app to empower people to… · bluesmart.com | acquired |
| 2011-06-01 | Automatic connects your car to the rest of your digital life. · automatic.com | acquired |
| 2011-06-01 | Powering scientific outsourcing · scienceexchange.com | acquired |
| 2020-01-01 | RNA medicines for liver diseases · ochre-bio.com | still up |
| 2018-06-01 | AIoT monitoring, workflow, and evidence systems for regulated labs. · ilabservice.ai | still up |
| 2022-01-01 | Bluetooth to Space · hubble.com | still up |
| 2019-01-01 | Unlocking the utility of genomics for the world. · voltalabs.com | still up |
| 2021-01-01 | Robots that automate the everyday tasks of microbiologists. · reshapebiotech.com | still up |
| 2020-01-01 | maximizing biomass on low quality land · livingcarbon.com | still up |
| 2015-01-01 | Personalized drug discovery for blood cancer. · notablelabs.com | acquired |
| 2019-01-01 | YCOverview Reshaping industrial quality with AI, hardware, and software · overview.ai | still up |
| 2013-06-01 | Location intelligence platform · estimote.com | still up |
| 2018-01-01 | We grow cells for biotech companies. · culturebiosciences.com | still up |
| 2018-06-01 | Next-gen ingredients to decarbonize consumer products, starting w/… · c16bio.com | still up |
| 2019-01-01 | YCTermius Termius is an SSH client with team collaboration features · termius.com | still up |
| 2020-06-01 | We make unmakeable proteins with radical advanced biomanufacturing. · futurefields.io | still up |
| 2018-01-01 | Engineering next-generation, brain-penetrant cancer therapies. · reverielabs.com | gone |
| 2016-01-01 | YCUnima Fast and low-cost diagnostics for real time disease surveillance · unimadx.com | gone |
| 2018-06-01 | YCMytos Robotic human cell manufacturing · mytos.bio | still up |
| 2022-01-01 | YCInvert Data analytics software for biomanufacturing. · invertbio.com | still up |
| 2020-06-01 | YCSeam API for IoT Devices · seam.co | still up |
| 2022-06-01 | YCChariot A payment network connecting nonprofits to the $326B in DAFs · givechariot.com | still up |
| 2021-06-01 | Unlocking the next generation of mRNA medicines · sensible.bio | still up |
| 2017-01-01 | Next-generation mRNA platform to solve cancer, COVID and climate. · helixnano.com | still up |
| 2020-06-01 | YCBlissway The tolling industry’s prime tech infrastructure · blissway.com | still up |
| 2018-01-01 | YCZBiotics ZBiotics makes genetically engineered probiotics. · zbiotics.com | still up |
| 2021-06-01 | Using the immune system to cure disease · parallel.bio | still up |
| 2024-01-01 | AI Inference Platform for Drug Discovery · tamarind.bio | still up |
| 2020-01-01 | YCPowerX AI powered sensors that save energy, water and emissions · powerx.co | acquired |
| 2019-06-01 | Arpeggio Bio develops drugs targeting transcription factors using AI… · arpeggiobio.com | still up |
| 2025-01-01 | Agents for Accelerated Clinical Trial Design · delineate.pro | still up |
| 2018-01-01 | YCOvipost Automated insect farming · ovipost.com | gone |
| 2020-06-01 | Kernal is creating mRNA 2.0 therapies that work in specific cells · kernalbio.com | still up |
| 2018-06-01 | Fermentation-derived natural products to solve health problems · cbthera.com | still up |
| 2023-06-01 | YCNumen Engineering a future without cancer deaths. · numen.com | still up |
| 2019-01-01 | Patient Intelligence Platform for Genetic Disease · probablygenetic.com | still up |
| 2014-06-01 | YCRavti Software to track, manage, and procure HVAC for commercial real… · ravti.com | acquired |
| 2021-06-01 | Discovering drugs that target the DNA regulome · talus.bio | still up |
| 2021-06-01 | YCScispot The Best Data Infrastructure for Biotechs · scispot.io | still up |
| 2021-06-01 | Diversifying precision cancer diagnostics and treatments · yemaachi.com | still up |
| 2014-06-01 | Data platform for metagenomics and the microbiome. · onecodex.com | acquired |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.