You asked about Genomics
33 people built something like it. 5 are gone.
That is 19% of the ones whose fate we could settle, against 23% across the whole register. 7 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2017-06-01 | The genetic testing platform detecting and measuring disease. · billiontoone.com | acquired |
| 2019-06-01 | Discovering the true signals of disease to power life-changing drugs. · sequencebio.com | still up |
| 2020-01-01 | RNA medicines for liver diseases · ochre-bio.com | still up |
| 2015-06-01 | We use human data and AI to develop better drugs faster. · vergegenomics.com | still up |
| 2019-01-01 | Unlocking the utility of genomics for the world. · voltalabs.com | still up |
| 2019-01-01 | YC54Gene Precision medicine for Africans and the global population · 54gene.com | gone |
| 2022-01-01 | Unleashing the potential of DNA and RNA based therapies using AI · whitelabgx.com | still up |
| 2016-06-01 | Bringing 3rd generation, nanopore sequencing to healthcare to solve… · shieldbio.com | gone |
| 2017-06-01 | CCG.ai empowers clinicians to make personalised treatment strategies… · ccg.ai | gone |
| 2017-01-01 | Next-generation mRNA platform to solve cancer, COVID and climate. · helixnano.com | still up |
| 2019-06-01 | Arpeggio Bio develops drugs targeting transcription factors using AI… · arpeggiobio.com | still up |
| 2020-06-01 | Kernal is creating mRNA 2.0 therapies that work in specific cells · kernalbio.com | still up |
| 2019-01-01 | Patient Intelligence Platform for Genetic Disease · probablygenetic.com | still up |
| 2021-06-01 | Discovering drugs that target the DNA regulome · talus.bio | still up |
| 2014-06-01 | Data platform for metagenomics and the microbiome. · onecodex.com | acquired |
| 2021-06-01 | DNA App Store · genomelink.io | still up |
| 2022-01-01 | Software to launch and integrate genetics into clinical care · nestgenomics.com | still up |
| 2015-06-01 | Cofactor closes the precision medicine gap with predictive diagnostics · cofactorgenomics.com | still up |
| 2017-06-01 | Rev is a biotechnology company creating better plants. · revgenomics.com | still up |
| 2016-01-01 | Novel long-read DNA sequencing technology · loopgenomics.com | acquired |
| 2021-06-01 | YCMable First personalized migraine clinic using genetics and telehealth. · trymable.com | acquired |
| 2019-01-01 | Large Scale Genomic Data Mining Software · spiralgenetics.com | gone |
| 2020-01-01 | We’re creating programmable therapies · felixbt.com | gone |
| 2018-06-01 | Utilizing monogenic disorders to inform and solve highly complex… · circumventpharmaceuticals.com | still up |
| 2019-01-01 | YCXGenomes XGenomes is building the sequencing technology of the future. · xgenomes.com | still up |
| 2021-06-01 | A platform to make artificial viruses as cancer therapeutics. · humanegenomics.com | still up |
| 2018-06-01 | New clinical tests for managing autoimmune treatments. · coralgenomics.com | acquired |
| 2025-09-01 | A Foundation Model for Microbial Communities. · anto.bio | still up |
| 2019-06-01 | Using DNA to store data. · kernsystems.com | still up |
| 2026-06-01 | YCGamgee Curing cancer. Starting with dogs. · gamgee.io | still up |
| 2016-01-01 | Diagnostic platform for early detection of liver disease · luministlabs.com | acquired |
| 2017-01-01 | Sigma Genetics is a biotechnology company that is building… · sigmagenetics.com | still up |
| 2020-01-01 | The better way to run single cell genomics · dropprintgen.com | acquired |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.