You asked about Genetic Engineering
734 people built something like it. 121 are gone.
That is 20% of the ones whose fate we could settle, against 23% across the whole register. 115 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2025-09-01 | YCPerseus Applied Lab focused on Search in Latent Spaces. · perseus.computer | still up |
| 2023-06-01 | Genetically engineering plants for disease resistance. · ohmicbiosciences.com | still up |
| 2014-06-01 | We enable cheaper, faster, and better genetic engineering of plants.… · taxa.com | gone |
| 2019-01-01 | Online engineering college for India. Learn technical skills & get… · skill-lync.com | still up |
| 2015-01-01 | YCGitLab A complete DevOps platform delivered as a single application. · gitlab.com | acquired |
| 2010-01-01 | The first all-in-one operating system for marketing · optimizely.com | acquired |
| 2013-01-01 | YCFivetran The leader in automated data movement · fivetran.com | still up |
| 2017-06-01 | The first public safety operating system that eliminates crime. · flocksafety.com | still up |
| 2010-06-01 | Real-time visibility into critical apps and services all in one place. · pagerduty.com | acquired |
| 2014-01-01 | YCAlgolia A developer-friendly and enterprise-grade search API. · algolia.com | still up |
| 2016-06-01 | YCScale AI Data-centric infrastructure to accelerate the development of AI · scale.com | still up |
| 2016-06-01 | YCBird The world’s largest omnichannel communications platform · bird.com | still up |
| 2019-06-01 | YCTRM Labs TRM is building a safer world for billions of people. · trmlabs.com | still up |
| 2022-10-20 | playerzero.app | unverified |
| 2017-06-01 | The genetic testing platform detecting and measuring disease. · billiontoone.com | acquired |
| 2016-01-01 | YCSendbird The AI agent that doesn’t just support, it delights. · sendbird.com | still up |
| 2016-01-01 | Agentic Observability Platform for Mobile · luciq.ai | still up |
| 2012-01-01 | YCRescale High Performance Computing Built for the Cloud · rescale.com | still up |
| 2014-01-01 | YCPovio Engineering and Design that Fuels Startup Success · povio.com | still up |
| 2016-01-01 | AI + Robotics for the Built World · geckorobotics.com | still up |
| 2012-01-01 | YCAuthy Authy is a Two-Factor Authentication platform for developers · authy.com | acquired |
| 2011-06-01 | YCApollo Apollo helps engineering teams accelerate delivery · apollographql.com | still up |
| 2023-08-07 | chainforge.ai | still up |
| 2015-01-01 | YCMezmo Observability platform to control all of your log data · mezmo.com | still up |
| 2022-03-16 | devcycle.com | still up |
| 2018-06-01 | Build and grow your app business · revenuecat.com | still up |
| 2019-06-01 | YCCoLab Human and AI design review for hardware · colabsoftware.com | still up |
| 2021-01-01 | YCGigs The OS for Embedded Telecom · gigs.com | still up |
| 2015-06-01 | YCZeplin Deliver on the Promise of Design · zeplin.io | still up |
| 2023-05-09 | engineeringbookclub.com | still up |
| 2020-06-01 | YCSupabase Build in a weekend. Scale to millions. · supabase.com | still up |
| 2016-01-01 | YCDeepgram Building foundational AI for speech transcription and understanding. · deepgram.com | still up |
| 2016-01-01 | YCGitPrime Visibility and analytics for software development leaders. · gitprime.com | acquired |
| 2020-06-01 | YCRoboflow 🖼️ Give your software the sense of sight. · roboflow.com | still up |
| 2021-01-01 | YCAlokai Frontend Platform for eCommerce · alokai.com | still up |
| 2015-06-01 | The only R&D data cloud for life sciences · tetrascience.com | still up |
| 2020-01-01 | YCAirbyte Context layer for production-grade AI agents · airbyte.com | still up |
| 2018-01-01 | YCShogun Shogun empowers brands to create exceptional ecommerce experience. · getshogun.com | still up |
| 2022-01-01 | AI-native operating system for home service businesses · broccoli.com | still up |
| 2023-04-02 | prompt-engineering-jobs.com | gone |
| 2019-01-01 | Superb AI provides end-to-end computer vision MLOps platform · superb-ai.com | still up |
| 2022-01-01 | YCMintlify The intelligent knowledge platform · mintlify.com | still up |
| 2020-06-01 | YCFinch Finch is the Employment Data Platform · tryfinch.com | still up |
| 2022-12-14 | devblogs.co | still up |
| 2021-01-30 | lolsolved.gg | still up |
| 2018-01-01 | YCReplit Collaborative in-browser IDE · replit.com | still up |
| 2021-06-01 | YCVerihubs AI-powered Deepfake Detection · verihubs.com | still up |
| 2019-06-01 | YCEmbrace Modern user-focused observability built on OpenTelemetry · embrace.io | acquired |
| 2021-01-01 | YCMindee AI Document Understanding API · mindee.com | still up |
| 2020-06-01 | YCDecentro API Platform for Banking Integrations (Plaid for India and APAC) · decentro.tech | still up |
| 2019-06-01 | The design system layer for coding agents · zeroheight.com | still up |
| 2021-01-01 | Application Development Platform (Native Mobile + Web Apps) · flutterflow.io | still up |
| 2014-01-01 | YCDevCycle Feature Flag Management Built for Developers · devcycle.com | acquired |
| 2016-01-01 | YCChatfuel Platform to easily create chatbots to engage with audiences on… · chatfuel.com | still up |
| 2015-01-01 | YCReadMe Beautiful, personalized, interactive developer hubs · readme.com | still up |
| 2013-01-01 | YCScuba Analytics for impatient people. · scuba.io | acquired |
| 2011-01-01 | YCMailgun Email API service. · mailgun.net | acquired |
| 2015-06-01 | YCGigster Build and manage distributed teams · gigster.com | acquired |
| 2007-06-01 | YCEivod eivod.com | gone |
| 2015-01-01 | Paperspace is a cloud platform for building and scaling AI… · paperspace.com | acquired |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.