You asked about Gene Therapy
115 people built something like it. 115 are gone.
That is 100% of the ones whose fate we could settle, against 23% across the whole register.
| Launched | What it was | Today |
|---|---|---|
| 2018-06-01 | Democratizing gene therapy by reinventing its manufacturing and… · perception.bio | gone |
| 2022-08-23 | pornpen.ai | gone |
| 2022-11-30 | thegist.ai | gone |
| 2022-04-19 | emacs.amodernist.com | gone |
| 2022-01-09 | squareqr.app | gone |
| 2022-01-31 | ideas-generator.com | gone |
| 2022-01-05 | nonnfts.com | gone |
| 2022-01-04 | qr-code.ai | gone |
| 2022-06-16 | snoolink.me | gone |
| 2022-09-21 | phantasmagoria.stavros.io | gone |
| 2022-06-10 | terragen.dev | gone |
| 2023-05-12 | logicloop.com | gone |
| 2023-08-23 | gentrace.ai | gone |
| 2023-08-13 | notyet.news | gone |
| 2023-08-17 | textify.storia.ai | gone |
| 2023-11-23 | mycyclopedia.co | gone |
| 2019-01-01 | YC54Gene Precision medicine for Africans and the global population · 54gene.com | gone |
| 2017-06-01 | Sunfolding builds next generation infrastructure for solar farms. By… · sunfolding.com | gone |
| 2018-01-01 | Engineering next-generation, brain-penetrant cancer therapies. · reverielabs.com | gone |
| 2021-03-09 | superroute.evergreen-labs.com | gone |
| 2016-06-01 | Bringing 3rd generation, nanopore sequencing to healthcare to solve… · shieldbio.com | gone |
| 2023-07-13 | resumine.io | gone |
| 2023-02-13 | designhat.ai | gone |
| 2022-03-22 | radishjs.com | gone |
| 2022-11-30 | rickandmortify.com | gone |
| 2021-07-13 | astrumnft.art | gone |
| 2023-09-09 | talebotai.com | gone |
| 2017-06-01 | Social Construct designs and assembles large apartment buildings
… · socialconstructco.com | gone |
| 2022-09-21 | niche.community | gone |
| 2023-11-27 | drawfast.io | gone |
| 2021-08-28 | prpl.dev | gone |
| 2021-01-07 | uniqueaiart.com | gone~35mo |
| 2023-10-06 | creativeautomatic.com | gone |
| 2023-04-04 | namique.xyz | gone |
| 2020-06-01 | AI.Fashion is the AI creative suite for the fashion industry. · ai.fashion | gone |
| 2023-03-09 | vocalvoters.com | gone |
| 2023-01-05 | barf.bt.ht | gone |
| 2022-11-19 | chat-example.langa.me | gone |
| 2022-06-01 | idearamen.com | gone |
| 2021-07-10 | canyouguess.art | gone |
| 2023-04-08 | qi.amalgamated.tech | gone |
| 2023-11-01 | skeletongenerator.com | gone |
| 2020-01-01 | We generate synthetic data for computer vision models. · zumolabs.ai | gone |
| 2019-01-01 | Large Scale Genomic Data Mining Software · spiralgenetics.com | gone |
| 2021-05-14 | series.slice.so | gone |
| 2021-07-06 | qrosscodes.com | gone |
| 2021-10-27 | rodb.io | gone |
| 2023-11-13 | demo.storywhisper.xyz | gone |
| 2023-03-26 | guided.rest | gone |
| 2023-08-21 | preview.steerlab.ai | gone |
| 2022-02-12 | rapidmock.com | gone |
| 2021-12-01 | galeras.io | gone |
| 2023-01-25 | genome.build | gone |
| 2021-04-07 | modmusicgen.com | gone |
| 2023-10-07 | checkfor.ai | gone |
| 2023-10-22 | bsri.blog | gone |
| 2023-05-07 | pixelfy.ai | gone |
| 2021-11-01 | mapps.makeall.dev | gone |
| 2021-11-05 | pdf2preview.chuanenlin.com | gone |
| 2023-04-06 | thatshallot.ai | gone |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.