You asked about IoT Security
44 people built something like it. 6 are gone.
That is 15% of the ones whose fate we could settle, against 23% across the whole register. 4 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2021-01-01 | YCTractian Physical AI for asset-heavy industries · tractian.com | still up |
| 2021-01-01 | YCCyble Cyble - World’s First Intelligence-Driven, AI-Native Security… · cyble.com | still up |
| 2021-01-01 | YCgaiia all-in-one operating system (OS) for telcos · gaiia.com | still up |
| 2021-06-01 | YCRootly AI-native on-call and incident response carefully crafted to help… · rootly.com | still up |
| 2021-01-01 | Robots that automate the everyday tasks of microbiologists. · reshapebiotech.com | still up |
| 2021-01-01 | YCauthzed Authorization Infrastructure securing AI at OpenAI, Zoom, & more · authzed.com | still up |
| 2021-06-01 | Unlocking the next generation of mRNA medicines · sensible.bio | still up |
| 2021-01-01 | AI-powered Compliance Platform for PCI 4, CCPA, HIPAA, CIPA, 50+ laws · feroot.com | still up |
| 2021-06-01 | Using the immune system to cure disease · parallel.bio | still up |
| 2021-06-01 | YCScispot The Best Data Infrastructure for Biotechs · scispot.io | still up |
| 2021-06-01 | Diversifying precision cancer diagnostics and treatments · yemaachi.com | still up |
| 2021-06-01 | Discovering drugs that target the DNA regulome · talus.bio | still up |
| 2021-01-01 | Discovering bispecific antibody drug-conjugates (BsADC) against cancer · valinktx.com | still up |
| 2021-06-01 | Security Delivery Platform to orchestrate AI agents for Service… · contraforce.com | still up |
| 2021-01-01 | GreaseBoss verifes industrial machinery is greased correctly · greaseboss.com.au | still up |
| 2021-06-01 | Patent-pending enzymes to break down common dietary triggers · fodzyme.com | still up |
| 2021-06-01 | We help nurses in nursing homes to be 30% more effective · momomedical.com | still up |
| 2021-06-01 | AI-driven mobile cybersecurity · mallocprivacy.com | still up |
| 2021-06-01 | YCidemeum AI-powered Application Control · idemeum.com | still up |
| 2021-06-01 | YCTarsal Data pipeline for your security data lake. · tarsal.co | acquired |
| 2021-06-01 | We make injections as easy as pushing a button! · pirouettepharma.com | still up |
| 2021-06-01 | Never code alone. · squire.ai | gone |
| 2021-06-01 | The foundation for the next era of biology · outputbio.com | still up |
| 2021-06-01 | Multi-targeted therapeutics to treat complex diseases · harmonicdiscovery.com | still up |
| 2021-06-01 | YCEpinoma We engineer proteins that control the operating system of biology. · epinoma.com | still up |
| 2021-06-01 | Cloud and Container Security Platform · cloudanix.com | still up |
| 2021-06-01 | Programmable biology company for psychoactive effect design · mindstate.design | still up |
| 2021-06-01 | Using protein coupling to build new therapies · catenabiosciences.com | still up |
| 2021-06-01 | AI-designed Affinity Reagents · medium.bio | still up |
| 2021-06-01 | YCTelivy Automate your cyber security risk assessments · telivy.com | acquired |
| 2021-01-01 | Discover drugs that control how much cells "squeeze" to treat disease · forcytebio.com | gone |
| 2021-01-01 | Genetic Medicine with Small Molecules · serna.bio | still up |
| 2021-06-01 | YCProtego We help companies recover lost revenue from chargebacks · protegosolutions.io | gone |
| 2021-06-01 | One-hour antibiotic sensitivity testing · astekdx.com | still up |
| 2021-06-01 | YCKeyri Secure fraud prevention and authentication platform for developers · keyri.com | acquired |
| 2021-01-01 | YCStacksi Automated Answers to Security Questionnaires · stacksi.com | acquired |
| 2021-06-01 | YCBLUUMBIO We make bacteria and plants that clean up pollution. · bluumbio.com | still up |
| 2021-06-01 | Web infra for AI agents · hyperbrowser.ai | still up |
| 2021-06-01 | Regulating the immune system to block cancer & autoimmune diseases · sfatherapeutics.com | still up |
| 2021-01-01 | Creating a New Class of Drugs to Address Incurable Autoimmune Diseases · entelexo.com | still up |
| 2021-01-01 | The solution for fine-grained access control in web3 · slashauth.com | gone |
| 2021-01-01 | Bioengineered kidneys for patients with kidney failure · trestlebio.com | still up |
| 2021-01-01 | YCObserva Catch accidental database exposures before the bad guys · observa.com | gone |
| 2021-06-01 | Technologies for scaling up cultured/clean meat production · micromeat.com | gone |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.