You asked about Industrial Bio
74 people built something like it. 8 are gone.
That is 12% of the ones whose fate we could settle, against 23% across the whole register. 5 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2021-01-01 | Robots that automate the everyday tasks of microbiologists. · reshapebiotech.com | still up |
| 2021-01-01 | Tasty and scalable cultivated meat at price parity · orbillion.com | acquired |
| 2021-06-01 | YCBLUUMBIO We make bacteria and plants that clean up pollution. · bluumbio.com | still up |
| 2021-01-01 | Bioengineered kidneys for patients with kidney failure · trestlebio.com | still up |
| 2021-06-01 | Technologies for scaling up cultured/clean meat production · micromeat.com | gone |
| 2021-01-01 | YCTractian Physical AI for asset-heavy industries · tractian.com | still up |
| 2021-01-01 | Mobile Energy Storage Technology · moxionpower.com | gone |
| 2021-01-01 | Seamless mobility to, through, and from space. It starts with 100%… · stokespace.com | still up |
| 2021-01-01 | YCGridware Protecting the grid today, preparing the grid for tomorrow · gridware.io | still up |
| 2021-01-01 | YCEnode Energy Orchestration Platform · enode.com | still up |
| 2021-01-01 | Software orchestrated mass production of plastics · atomic.industries | still up |
| 2021-01-01 | The lightest electric aircraft motors in the world. · h3x.tech | still up |
| 2021-01-01 | Physical AI for Warehouses and Factories · fluxauto.ai | still up |
| 2021-01-01 | YCAlbedo Full-stack VLEO satellite missions · albedo.com | still up |
| 2021-01-01 | YCRemora Carbon capture for vehicles · remoracarbon.com | still up |
| 2021-01-01 | YCREGENT All-electric seagliders for fast, affordable regional transportation · regentcraft.com | still up |
| 2021-06-01 | YCAbatable Carbon markets platform and solutions · abatable.com | still up |
| 2021-06-01 | On-demand auto maintenance & repairs · mechoautotech.com | still up |
| 2021-06-01 | Helping farmers maximize crop yield · instacrops.com | still up |
| 2021-06-01 | YCVedaBio CRISPR powered Diagnostics with results in minutes. · vedabio.com | still up |
| 2021-06-01 | Turning space into a transportation layer for Earth · inversionspace.com | still up |
| 2021-06-01 | YCAdaptyv We're building fully automated labs for protein engineering · adaptyvbio.com | still up |
| 2021-06-01 | Robots that build solar farms · chargerobotics.com | still up |
| 2021-01-01 | YCFaction Driverless electric vehicles at a fraction of the cost of a car. · faction.us | gone |
| 2021-06-01 | Unlocking the next generation of mRNA medicines · sensible.bio | still up |
| 2021-06-01 | Decarbonizing the fashion industry · carbonfact.com | still up |
| 2021-06-01 | Water risk mitigation for industrial sites · waterplan.com | still up |
| 2021-06-01 | Using the immune system to cure disease · parallel.bio | still up |
| 2021-06-01 | Low-cost, high-scale EV charging platform for apartments (and more). · heycharge.com | still up |
| 2021-06-01 | YCFerveret Nuclear-inspired cooling that turns wasted power into more AI compute · ferveret.com | still up |
| 2021-06-01 | Discovering drugs that target the DNA regulome · talus.bio | still up |
| 2021-06-01 | Diversifying precision cancer diagnostics and treatments · yemaachi.com | still up |
| 2021-06-01 | YCScispot The Best Data Infrastructure for Biotechs · scispot.io | still up |
| 2021-06-01 | Moving Things Around in Space, Imaging Space Objects When We're Not · turionspace.com | still up |
| 2021-01-01 | Discovering bispecific antibody drug-conjugates (BsADC) against cancer · valinktx.com | still up |
| 2021-01-01 | YCAurabeat Providing clean, safe, virus free air for homes, buildings and cars · aurabeattech.com | still up |
| 2021-06-01 | YCHeimdal Affordable and verified direct air carbon capture and storage · heimdalccu.com | gone |
| 2021-05-21 | proficience.io | gone |
| 2021-06-01 | Vertical takeoff and landing aircraft for major airlines · odysaviation.com | still up |
| 2021-06-01 | Near Space Flying Machines · kalamlabs.in | still up |
| 2021-06-01 | Patent-pending enzymes to break down common dietary triggers · fodzyme.com | still up |
| 2021-01-01 | YCPipeBio PipeBio is a SaaS bioinformatics platform to develop antibody drugs. · pipebio.com | acquired |
| 2021-01-01 | Electricity price forecasts for energy storage, ev charging, etc. · inbalanceresearch.com | acquired |
| 2021-01-01 | GreaseBoss verifes industrial machinery is greased correctly · greaseboss.com.au | still up |
| 2021-01-01 | We make satellites to image everywhere on Earth, every 15 minutes · albaorbital.com | still up |
| 2021-06-01 | YCRMFG Advanced Contract MFG for fast moving hardware companies · rmfg.com | still up |
| 2021-06-01 | YCEnerjazz Making electric vehicle batteries affordable · enerjazz.tech | still up |
| 2021-06-01 | We make injections as easy as pushing a button! · pirouettepharma.com | still up |
| 2021-06-01 | YCEpinoma We engineer proteins that control the operating system of biology. · epinoma.com | still up |
| 2021-06-01 | Orbital logistics: Unleashing space industry, from Earth to asteroids · transastra.com | still up |
| 2021-01-01 | YCBiodock Cloud AI microscopy automation · biodock.ai | still up |
| 2021-01-01 | YCBotBuilt We use robots to build houses. · botbuilt.com | still up |
| 2021-06-01 | The foundation for the next era of biology · outputbio.com | still up |
| 2021-06-01 | Multi-targeted therapeutics to treat complex diseases · harmonicdiscovery.com | still up |
| 2021-06-01 | Using protein coupling to build new therapies · catenabiosciences.com | still up |
| 2021-06-01 | Reducing energy costs & emissions in buildings. · kapacity.io | acquired |
| 2021-06-01 | Programmable biology company for psychoactive effect design · mindstate.design | still up |
| 2021-01-01 | YCNoya Radically reducing capital costs and build time for direct air capture · noya.co | gone |
| 2021-06-01 | AI-designed Affinity Reagents · medium.bio | still up |
| 2021-01-01 | Genetic Medicine with Small Molecules · serna.bio | still up |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.