You asked about Industrial Bio
25 people built something like it. 3 are gone.
That is 12% of the ones whose fate we could settle, against 23% across the whole register.
| Launched | What it was | Today |
|---|---|---|
| 2023-06-01 | Farm Genetics Made Easy - Using DNA and Software · feanixbio.com | still up |
| 2023-01-01 | Gen-AI Designed Enzymes for Pharmaceutical Innovation · pando.bio | still up |
| 2023-06-01 | Genetically engineering plants for disease resistance. · ohmicbiosciences.com | still up |
| 2023-06-01 | YCHyLight Unmanned airships for inspecting our critical assets · hylight.aero | still up |
| 2023-01-01 | YCProglix B2B Marketplace for Steel Raw Materials · proglix.com | still up |
| 2023-06-01 | YCNumen Engineering a future without cancer deaths. · numen.com | still up |
| 2023-06-01 | Live intelligence for biopharma teams. · mavenbio.com | still up |
| 2023-01-01 | Generative AI for protein design · diffuse.bio | still up |
| 2023-01-01 | Adventris makes cancer vaccines · adventris.com | still up |
| 2023-01-01 | YCMiracle Accelerate clinical trials with real-time, actionable insights · miracleml.com | still up |
| 2023-06-01 | Transform scientific data into discoveries · mantlebio.com | gone |
| 2023-06-01 | YCNectar Manage energy cost & usage with AI for facility & sustainability teams · nectarclimate.com | still up |
| 2023-01-01 | YCRadical Building persistent, high-performance infrastructure in the sky · radicalaero.com | still up |
| 2023-06-01 | Tracking methane emissions with satellites · orbio.earth | still up |
| 2023-01-01 | YCOhm Ohm helps engineering teams accelerate hardware development & testing. · ohm.ai | still up |
| 2023-01-01 | YCInvitris Creating new protein-based drugs at scale · invitris.com | still up |
| 2023-06-01 | YCNanograb Deliver genes to any cell with AI · nanograb.com | still up |
| 2023-01-01 | We teach your immune system to attack and cure cancer · modularit.bio | still up |
| 2023-01-01 | Emission free hydrogen electric aircraft · stralis.aero | still up |
| 2023-06-01 | YCGleam Automating Data Entry for Clinical Trials · joingleam.com | still up |
| 2023-06-01 | AI back office for food product quality teams · cognitioiq.com | still up |
| 2023-01-01 | AI for drug formulation · lavo.ai | gone |
| 2023-01-01 | Revolutionary, Modern Wing Sails · outsailtech.com | gone |
| 2023-01-01 | YCAtmeto We develop ML that optimizes how batteries in the grid store energy · atmeto.com | still up |
| 2023-06-01 | Building and Protecting an Exciting Future · singularityus.com | still up |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.