You asked about Industrial Bio
73 people built something like it. 7 are gone.
That is 10% of the ones whose fate we could settle, against 23% across the whole register. 5 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2021-01-01 | Robots that automate the everyday tasks of microbiologists. · reshapebiotech.com | still up |
| 2021-01-01 | Tasty and scalable cultivated meat at price parity · orbillion.com | acquired |
| 2021-06-01 | YCBLUUMBIO We make bacteria and plants that clean up pollution. · bluumbio.com | still up |
| 2021-01-01 | Bioengineered kidneys for patients with kidney failure · trestlebio.com | still up |
| 2021-06-01 | Technologies for scaling up cultured/clean meat production · micromeat.com | gone |
| 2021-01-01 | YCTractian Physical AI for asset-heavy industries · tractian.com | still up |
| 2021-01-01 | Mobile Energy Storage Technology · moxionpower.com | gone |
| 2021-01-01 | Seamless mobility to, through, and from space. It starts with 100%… · stokespace.com | still up |
| 2021-01-01 | YCGridware Protecting the grid today, preparing the grid for tomorrow · gridware.io | still up |
| 2021-01-01 | YCEnode Energy Orchestration Platform · enode.com | still up |
| 2021-01-01 | Software orchestrated mass production of plastics · atomic.industries | still up |
| 2021-01-01 | The lightest electric aircraft motors in the world. · h3x.tech | still up |
| 2021-01-01 | Physical AI for Warehouses and Factories · fluxauto.ai | still up |
| 2021-01-01 | YCAlbedo Full-stack VLEO satellite missions · albedo.com | still up |
| 2021-01-01 | YCRemora Carbon capture for vehicles · remoracarbon.com | still up |
| 2021-01-01 | YCREGENT All-electric seagliders for fast, affordable regional transportation · regentcraft.com | still up |
| 2021-06-01 | On-demand auto maintenance & repairs · mechoautotech.com | still up |
| 2021-06-01 | YCAbatable Carbon markets platform and solutions · abatable.com | still up |
| 2021-06-01 | Helping farmers maximize crop yield · instacrops.com | still up |
| 2021-06-01 | YCVedaBio CRISPR powered Diagnostics with results in minutes. · vedabio.com | still up |
| 2021-06-01 | Turning space into a transportation layer for Earth · inversionspace.com | still up |
| 2021-06-01 | YCAdaptyv We're building fully automated labs for protein engineering · adaptyvbio.com | still up |
| 2021-01-01 | YCFaction Driverless electric vehicles at a fraction of the cost of a car. · faction.us | gone |
| 2021-06-01 | Robots that build solar farms · chargerobotics.com | still up |
| 2021-06-01 | Unlocking the next generation of mRNA medicines · sensible.bio | still up |
| 2021-06-01 | Decarbonizing the fashion industry · carbonfact.com | still up |
| 2021-06-01 | Using the immune system to cure disease · parallel.bio | still up |
| 2021-06-01 | Water risk mitigation for industrial sites · waterplan.com | still up |
| 2021-06-01 | Low-cost, high-scale EV charging platform for apartments (and more). · heycharge.com | still up |
| 2021-06-01 | Diversifying precision cancer diagnostics and treatments · yemaachi.com | still up |
| 2021-06-01 | YCFerveret Nuclear-inspired cooling that turns wasted power into more AI compute · ferveret.com | still up |
| 2021-06-01 | YCScispot The Best Data Infrastructure for Biotechs · scispot.io | still up |
| 2021-06-01 | Discovering drugs that target the DNA regulome · talus.bio | still up |
| 2021-01-01 | Discovering bispecific antibody drug-conjugates (BsADC) against cancer · valinktx.com | still up |
| 2021-06-01 | Moving Things Around in Space, Imaging Space Objects When We're Not · turionspace.com | still up |
| 2021-06-01 | YCHeimdal Affordable and verified direct air carbon capture and storage · heimdalccu.com | gone |
| 2021-01-01 | YCAurabeat Providing clean, safe, virus free air for homes, buildings and cars · aurabeattech.com | still up |
| 2021-06-01 | Vertical takeoff and landing aircraft for major airlines · odysaviation.com | still up |
| 2021-06-01 | Near Space Flying Machines · kalamlabs.in | still up |
| 2021-06-01 | Patent-pending enzymes to break down common dietary triggers · fodzyme.com | still up |
| 2021-01-01 | Electricity price forecasts for energy storage, ev charging, etc. · inbalanceresearch.com | acquired |
| 2021-01-01 | GreaseBoss verifes industrial machinery is greased correctly · greaseboss.com.au | still up |
| 2021-01-01 | YCPipeBio PipeBio is a SaaS bioinformatics platform to develop antibody drugs. · pipebio.com | acquired |
| 2021-01-01 | We make satellites to image everywhere on Earth, every 15 minutes · albaorbital.com | still up |
| 2021-06-01 | We make injections as easy as pushing a button! · pirouettepharma.com | still up |
| 2021-06-01 | YCRMFG Advanced Contract MFG for fast moving hardware companies · rmfg.com | still up |
| 2021-06-01 | YCEnerjazz Making electric vehicle batteries affordable · enerjazz.tech | still up |
| 2021-01-01 | YCBiodock Cloud AI microscopy automation · biodock.ai | still up |
| 2021-06-01 | Orbital logistics: Unleashing space industry, from Earth to asteroids · transastra.com | still up |
| 2021-06-01 | The foundation for the next era of biology · outputbio.com | still up |
| 2021-06-01 | Multi-targeted therapeutics to treat complex diseases · harmonicdiscovery.com | still up |
| 2021-06-01 | YCEpinoma We engineer proteins that control the operating system of biology. · epinoma.com | still up |
| 2021-01-01 | YCBotBuilt We use robots to build houses. · botbuilt.com | still up |
| 2021-01-01 | YCNoya Radically reducing capital costs and build time for direct air capture · noya.co | gone |
| 2021-06-01 | Using protein coupling to build new therapies · catenabiosciences.com | still up |
| 2021-06-01 | Programmable biology company for psychoactive effect design · mindstate.design | still up |
| 2021-06-01 | Reducing energy costs & emissions in buildings. · kapacity.io | acquired |
| 2021-06-01 | AI-designed Affinity Reagents · medium.bio | still up |
| 2021-01-01 | YCBlink Same-day delivery for e-commerce companies in Europe. · blinklastmile.com | gone |
| 2021-06-01 | A platform to make artificial viruses as cancer therapeutics. · humanegenomics.com | still up |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.