You asked about Industrial Bio
642 people built something like it. 79 are gone.
That is 13% of the ones whose fate we could settle, against 23% across the whole register. 49 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2014-06-01 | Our mission is to make biology easier to engineer. · ginkgobioworks.com | acquired |
| 2017-01-01 | YCSolugen Decarbonizing the chemicals industry. · solugen.com | still up |
| 2017-06-01 | Turning food waste into Biochar to remove CO2 from the atmsophere · releaf.africa | still up |
| 2020-01-01 | Next-generation DNA synthesis using enzymes · ansabio.com | still up |
| 2016-01-01 | YCLygos Lygos engineers yeast to convert sugar into high-value industrial… · lygos.com | still up |
| 2020-01-01 | Foundation models and autonomous chambers for plant biology · urbankisaan.com | still up |
| 2019-01-01 | Unlocking the utility of genomics for the world. · voltalabs.com | still up |
| 2018-01-01 | We grow cells for biotech companies. · culturebiosciences.com | still up |
| 2021-01-01 | Robots that automate the everyday tasks of microbiologists. · reshapebiotech.com | still up |
| 2020-01-01 | maximizing biomass on low quality land · livingcarbon.com | still up |
| 2018-06-01 | Next-gen ingredients to decarbonize consumer products, starting w/… · c16bio.com | still up |
| 2020-06-01 | We make unmakeable proteins with radical advanced biomanufacturing. · futurefields.io | still up |
| 2020-01-01 | Makes guilt-free plastics from food waste · genecis.co | still up |
| 2018-06-01 | YCMytos Robotic human cell manufacturing · mytos.bio | still up |
| 2018-06-01 | YC64x Bio Enabling next generation medicines. A comprehensive platform and… · 64xbio.com | still up |
| 2022-01-01 | YCInvert Data analytics software for biomanufacturing. · invertbio.com | still up |
| 2020-06-01 | YCKingdom Clinically-validated ingredients from natural microbes · kingdomsuperculture.com | still up |
| 2018-01-01 | YCOvipost Automated insect farming · ovipost.com | gone |
| 2020-06-01 | Impossible foods of seafood. · currentfoods.com | acquired |
| 2018-06-01 | Fermentation-derived natural products to solve health problems · cbthera.com | still up |
| 2019-06-01 | boostbiomes.com | gone |
| 2018-06-01 | Rebellyous Foods is a food manufacturing technology and production… · rebellyous.com | still up |
| 2015-01-01 | We design and build microbes to make chemicals greener at lower cost. · imicrobes.com | still up |
| 2022-06-01 | YCALT TEX Biodegradable and carbon neutral textiles, engineered from food waste. · thealttex.com | still up |
| 2022-06-01 | We recycle plastic using engineered enzymes · birchbiosciences.com | still up |
| 2022-01-01 | We make carbon negative chemicals from CO2 using fermentation · phasebiolabs.com | still up |
| 2019-01-01 | Shiok Meats is a cell-based clean shrimp company, the first of its… · shiokmeats.com | acquired |
| 2021-01-01 | Tasty and scalable cultivated meat at price parity · orbillion.com | acquired |
| 2022-01-01 | We stop cows from burping methane. · alga.bio | still up |
| 2022-01-01 | Making 'REAL' Cow and Human Milk! · unrealmilk.com | still up |
| 2023-01-01 | Gen-AI Designed Enzymes for Pharmaceutical Innovation · pando.bio | still up |
| 2020-01-01 | Volumetric builds living multicellular tissues with a focus on the… · volumetricbio.com | acquired |
| 2023-06-01 | Farm Genetics Made Easy - Using DNA and Software · feanixbio.com | still up |
| 2020-06-01 | YCRarebird Elevating mental health to be a part of your daily coffee ritual. · rarebird.coffee | still up |
| 2024-06-01 | YCACX Next-generation biocides for sustainable agriculture at scale · acxtherapeutics.com | still up |
| 2019-06-01 | YCShiru Shiru leverages ML to create proteins to feed the world sustainably. · shiru.com | still up |
| 2024-06-01 | Enzyme design models. · ligo.bio | still up |
| 2021-06-01 | YCBLUUMBIO We make bacteria and plants that clean up pollution. · bluumbio.com | still up |
| 2016-06-01 | YCSynvivia Synvivia applies chemical control over cell behavior · synvivia.com | still up |
| 2026-06-01 | YCMolagri Resistance free pesticides. · molagri.com | still up |
| 2019-06-01 | Using DNA to store data. · kernsystems.com | still up |
| 2026-09-01 | Maximum information per experiment, minimum experiments per conclusion · halmoslabs.com | still up |
| 2024-06-01 | YC1849 bio Engineering microbes for miners to unlock billions in trapped metal · 1849.bio | still up |
| 2026-06-01 | Building robots to automate wetlabs · neuromorphic.vision | still up |
| 2025-06-01 | AI infrastructure for biosecurity · twentytwo.bio | still up |
| 2025-06-01 | Implantable microchips and AI for cattle monitoring · nexa.farm | acquired |
| 2026-09-01 | Embodied Scientific Intelligence · superradiant.co | still up |
| 2021-01-01 | Bioengineered kidneys for patients with kidney failure · trestlebio.com | still up |
| 2023-06-01 | Genetically engineering plants for disease resistance. · ohmicbiosciences.com | still up |
| 2015-01-01 | YC20n Using AI to predict biochemistry for manufacturing and therapeutics · 20n.com | gone |
| 2024-01-01 | YCRelari Building dexterous robots that learn from human biomechanics · relari.ai | still up |
| 2026-06-01 | Frontier grows scalable biological brains as an ML training substrate · frontier.site | still up |
| 2021-06-01 | Technologies for scaling up cultured/clean meat production · micromeat.com | gone |
| 2018-06-01 | dairy reinvented from plants · sperofoods.co | gone |
| 2014-01-01 | YCCruise Self-driving cars. · getcruise.com | acquired |
| 2016-01-01 | Building humanity’s multiplanetary future. · relativityspace.com | still up |
| 2012-06-01 | Unlocking the power of biotech with modern software for modern science · benchling.com | still up |
| 2021-01-01 | YCTractian Physical AI for asset-heavy industries · tractian.com | still up |
| 2016-01-01 | YCAstranis Advanced satellites for high orbits. · astranis.com | still up |
| 2021-01-01 | Mobile Energy Storage Technology · moxionpower.com | gone |
How this compares
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.