You asked about Genetic Engineering
88 people built something like it. 10 are gone.
That is 14% of the ones whose fate we could settle, against 23% across the whole register. 16 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2023-06-01 | Genetically engineering plants for disease resistance. · ohmicbiosciences.com | still up |
| 2023-01-01 | YCResend Email for developers · resend.com | still up |
| 2023-01-01 | YCPirros AI Platform for Architects and Engineers · pirros.com | still up |
| 2023-01-01 | YCFern Instantly offer SDKs and API Docs · buildwithfern.com | acquired |
| 2023-06-01 | YCGiga AI Support Agent for Enterprises. · giga.ai | still up |
| 2023-01-01 | YCClueso Create beautiful videos & docs for any product or process in minutes · clueso.io | still up |
| 2023-01-01 | YCVellum vellum.ai | still up |
| 2023-01-01 | YCDepot Software delivery built for machine scale. · depot.dev | still up |
| 2023-06-01 | YCTiptap The open-source document editor for humans and AI agents. · tiptap.dev | still up |
| 2023-01-01 | YCLangfuse Open source LLM engineering platform · langfuse.com | acquired |
| 2023-06-01 | YCNumen Engineering a future without cancer deaths. · numen.com | still up |
| 2023-01-01 | YCInkeep Build AI Agent teammates and automations in code or no-code · inkeep.com | still up |
| 2023-01-01 | YCVersori Agentic integrations & automations for enterprise · versori.com | acquired |
| 2023-06-01 | YCArtie Software that streams data from databases to warehouses in real-time · artie.com | still up |
| 2023-06-01 | The GPU Cloud Marketplace · shadeform.ai | still up |
| 2023-01-01 | YCPierre Pierre is a new, opinionated, git platform. · pierre.co | still up |
| 2023-06-01 | YCrefine Open-source Retool for enterprise · refine.dev | still up |
| 2023-06-01 | AI for Government Contracting. · sweetspot.so | still up |
| 2023-01-01 | Go from idea to production with AI. · magicpatterns.com | still up |
| 2023-01-01 | Build and deploy fully‑managed AI agents and workflows · trigger.dev | still up |
| 2023-01-01 | YCIcePanel Design and explain complex software architecture. · icepanel.io | still up |
| 2023-06-01 | YCTempo Visual Editor for React, powered by AI · tempo.new | still up |
| 2023-06-01 | YCSilimate Fast, efficient agents for chip design and debug · silimate.com | still up |
| 2023-01-01 | YCDrDroid Your best friend in production. · drdroid.io | still up |
| 2023-01-01 | The open source, fullstack monitoring platform: stop guessing why… · highlight.io | acquired |
| 2023-01-01 | Phone AI that Captures Every Dealership Revenue Opportunity · shortloop.dev | still up |
| 2023-01-01 | YCFastgen Webflow for the Backend · fastgen.com | still up |
| 2023-06-01 | YCSID AI research lab for retrieval · sid.ai | still up |
| 2023-06-01 | YCSpine AI Manage a swarm of AI agents to get real work done · getspine.ai | still up |
| 2023-01-01 | YCRelace Models and infra for coding agents · relace.ai | still up |
| 2023-01-01 | YCSkyhook PaaS-like experience with the power of Kubernetes, on your cloud · skyhook.io | still up |
| 2023-06-01 | YCCedalio AI agents that automate AP, procurement, and finance · cedalio.com | still up |
| 2023-01-01 | YCOhm Ohm helps engineering teams accelerate hardware development & testing. · ohm.ai | still up |
| 2023-01-01 | YCNango A single API for all your integrations · nango.dev | still up |
| 2023-01-01 | YCHoneydew The home for shared data logic · honeydew.ai | still up |
| 2023-01-01 | YCKeep The open-source AIOps platform · keephq.dev | acquired |
| 2023-01-01 | YCLume Speed up customer implementation with AI · lume.ai | acquired |
| 2023-06-01 | AI for ASIC Design Verification · bronco.ai | still up |
| 2023-01-01 | AI-powered game translation. · magnaplay.com | still up |
| 2023-01-01 | AI agents for end-to-end testing · trynarrative.com | still up |
| 2023-06-01 | The publishing layer for the agentic internet · structuredlabs.com | gone |
| 2023-01-01 | YCLynx AI platform for investigating and resolving engineering incidents · uselynx.ai | gone |
| 2023-06-01 | Farm Genetics Made Easy - Using DNA and Software · feanixbio.com | still up |
| 2023-06-01 | Open source GenAI development platform · flowiseai.com | acquired |
| 2023-06-01 | YCSweep The best AI coding assistant for JetBrains · sweep.dev | still up |
| 2023-01-01 | YCFrigade AI-powered product assistance for modern software teams · frigade.com | still up |
| 2023-01-01 | The interface for your database · outerbase.com | acquired |
| 2023-06-01 | Web, Desktop, and Mobile apps with one codebase in Rust · dioxuslabs.com | acquired |
| 2023-06-01 | Aide is an AI-native , privacy-first IDE built on top of VSCode · aide.dev | gone |
| 2023-06-01 | The API for LLM tool use · opentools.com | still up |
| 2023-01-01 | Automating root cause analysis with generative AI · wildmoose.ai | still up |
| 2023-01-01 | YCVersive AI-first user research platform · getversive.com | still up |
| 2023-01-01 | Design and build great interfaces · designbase.com | still up |
| 2023-06-01 | YCTalc Event extraction for Medical Researchers · talc.ai | still up |
| 2023-06-01 | The Data Platform for Mission‑Critical Systems · zeloscloud.io | still up |
| 2023-01-01 | YCDream3D We build tools to help humanity predict the future. · dream3d.com | still up |
| 2023-01-01 | YCCardinal Your AI product backlog · cardinalapp.io | acquired |
| 2023-06-01 | YCInconvo Build chat-with-data agents for customer-facing applications · inconvo.com | still up |
| 2023-06-01 | YCInari Your junior AI product manager · useinari.com | acquired |
| 2023-01-01 | YCDashdive Break down AI and cloud costs by feature and customer · dashdive.com | acquired |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.