You asked about Gene Therapy
54 people built something like it. 7 are gone.
That is 14% of the ones whose fate we could settle, against 23% across the whole register. 4 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2022-01-01 | Unleashing the potential of DNA and RNA based therapies using AI · whitelabgx.com | still up |
| 2022-01-01 | Empowering Mass Spec for Biotech and Beyond · andsonbiotech.com | still up |
| 2022-01-01 | YCHumand All-in-one app for internal communication and HR · humand.co | still up |
| 2022-06-01 | YCJuicebox AI-powered talent sourcing for recruiters · juicebox.ai | still up |
| 2022-01-01 | YCGovDash AI platform to win and run government contracts · govdash.com | still up |
| 2022-01-01 | YCBotCity Observability and Governance for AI-Generated Python scripts. · botcity.dev | still up |
| 2022-01-01 | YCLanceDB Open-source, serverless vectordb for production-scale generative AI · lancedb.com | still up |
| 2022-01-01 | Virtualizing brick-mortar infrastructures of clinics w/ generative AI · ankr.us | still up |
| 2022-06-01 | Healthcare data infrastructure for next generation care delivery. · metriport.com | still up |
| 2022-06-01 | General Autonomy for Industrial Vehicles · polymathrobotics.com | still up |
| 2022-01-01 | Software to launch and integrate genetics into clinical care · nestgenomics.com | still up |
| 2022-01-01 | Liability insurance for generative AI and AI Agents · armilla.ai | still up |
| 2022-06-01 | YCFini Fini | Automate 80% of enterprise support with AI agents · usefini.com | still up |
| 2022-01-01 | YCKular AI Lead Generator · kular.ai | still up |
| 2022-06-01 | YCLayerup Agentic AI OS for Financial Services and Insurance · uselayerup.com | still up |
| 2022-01-01 | Next-generation, modular electric vehicles · olympianmotors.com | still up |
| 2022-01-01 | A modern and more accessible private bank for the new generation · onyxprivate.com | acquired |
| 2022-01-01 | Potent, durable, and redosable non-viral genetic medicines · engagebio.com | acquired |
| 2022-01-01 | YCDart The work and agent management platform · dartai.com | still up |
| 2022-06-01 | AI-powered business matchmaking · namecard.ai | still up |
| 2022-01-01 | YCgoodfin Building the next generation of wealth · goodfin.com | still up |
| 2022-01-01 | YCStrac Data Discovery, DLP, DSPM for SaaS, Cloud, Gen AI & Endpoints · strac.io | still up |
| 2022-01-01 | YCBobidi Restaurant Loyalty Using Quiz · upswell.ai | still up |
| 2022-06-01 | Combinations therapy by rational design · serinus.bio | still up |
| 2022-06-01 | Turn user feedback to product insights · monterey.ai | acquired |
| 2022-01-01 | YCNophin AI Deal Screening Analyst for Commercial Real Estate Acquisitions · nophin.com | gone |
| 2022-06-01 | YCWolfia We help security, legal and sales teams answer customer questions · wolfia.com | still up |
| 2022-06-01 | YCAd Army Generate, iterate, and ship AI ad creatives faster · ad.army | still up |
| 2022-06-01 | Building self-programming machines · mayalabs.io | still up |
| 2022-01-01 | YCToko Learn English by speaking with an AI · tokotutor.com | still up |
| 2022-01-01 | Financing the next-generation of infrastructure projects · perlstreet.com | still up |
| 2022-06-01 | YCPhind AI search engine · phind.com | gone |
| 2022-06-01 | Helping realtors showcase the full potential of their properties · applydesign.io | still up |
| 2022-06-01 | YCQuinn Your biopharma team, from molecule design to portfolio strategy · quinnbio.com | still up |
| 2022-01-01 | Oral drugs to halt neurodegeneration · origamitherapeutics.com | still up |
| 2022-06-01 | API for Retrieval Augmented Generation · superpowered.ai | gone |
| 2022-01-01 | YCDioptra Automated contract review with AI · dioptra.ai | acquired |
| 2022-06-01 | YCCAPSULE Buy anything you find on social media · shopcapsule.ai | gone |
| 2022-06-01 | AI Automation for Therapy Practices · getsolum.com | still up |
| 2022-06-01 | AI Sales Rep for Website Intent Signals · penguinai.app | gone |
| 2022-06-01 | YCDialect AI copilot for forms, questionnaires & RFX · usedialect.com | gone |
| 2022-06-01 | YCPoly Intelligent Personal Cloud Storage · poly.app | still up |
| 2022-01-01 | YCNearWave Helping physicians select the right therapy for breast cancer patients · nearwave.co | still up |
| 2022-01-01 | YCTop Road Payments & analytics for apps in the OpenAI GPT Store · toproad.ai | still up |
| 2022-06-01 | Your autonomous motion designer that turns every feature into a… · impractical.ai | still up |
| 2022-06-01 | We enable landlords to generate income from solar panels. · wandsolar.com | still up |
| 2022-06-01 | YCMercator AI-assisted data analytics · mercator.tech | gone |
| 2022-01-01 | YCAndi AI Search for the Next Generation · andiai.com | still up |
| 2022-06-01 | Generative AI for administrative automation in healthcare · delfino.ai | still up |
| 2022-06-01 | YCTypeLess AI messaging API for smarter, faster communication. · apps.apple.com | still up |
| 2022-06-01 | Enabling Tissue Targeting of Therapies · eugittx.com | still up |
| 2022-06-01 | Dendritic cell-based platform for cancer therapy · guardian-bio.com | still up |
| 2022-01-01 | AI agents to build B2B datasets · promptloop.com | still up |
| 2022-06-01 | YCMidplane The safety layer between AI agents and your database · midplane.ai | still up |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.