You asked about Drug discovery
12 people built something like it. 1 is gone.
That is 9% of the ones whose fate we could settle, against 23% across the whole register. 1 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2022-01-01 | Unleashing the potential of DNA and RNA based therapies using AI · whitelabgx.com | still up |
| 2022-01-01 | Potent, durable, and redosable non-viral genetic medicines · engagebio.com | acquired |
| 2022-06-01 | Platform injectable gel based therapeutic for osteoarthritis · relevium-medical.com | still up |
| 2022-06-01 | YCQuinn Your biopharma team, from molecule design to portfolio strategy · quinnbio.com | still up |
| 2022-01-01 | Oral drugs to halt neurodegeneration · origamitherapeutics.com | still up |
| 2022-01-01 | Bioinformatics pipelines in the cloud · flowdeploy.com | gone |
| 2022-01-01 | Growing micro-organs to find new drugs · rosebudbiosciences.com | still up |
| 2022-01-01 | YCAlixia Targeting the Tumor Ecosystem to address cancer drug resistance. · alixia.com | still up |
| 2022-06-01 | YCKeylika Redefining the Standard of Care for Iron Deficiency Anemia · keylika.com | still up |
| 2022-01-01 | YCStrac Data Discovery, DLP, DSPM for SaaS, Cloud, Gen AI & Endpoints · strac.io | still up |
| 2022-01-01 | YCCellbyte AI Agents for Pharma Drug Launches · cellbyte.com | still up |
| 2022-06-01 | YCKemNet KemNet supplies reformulated drugs for specific groups of patients. · kemnet.ca | still up |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.