You asked about Data Science
439 people built something like it. 56 are gone.
That is 15% of the ones whose fate we could settle, against 23% across the whole register. 71 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2015-06-01 | The only R&D data cloud for life sciences · tetrascience.com | still up |
| 2016-06-01 | Bridging a world of consumer-permissioned credit data · novacredit.com | still up |
| 2015-01-01 | Data Versioning, Data Pipelines, and Data Lineage · pachyderm.com | acquired |
| 2019-01-01 | YCCentaur We Create Superior Data By Making Annotation Competitive · centaur.ai | still up |
| 2017-01-01 | Getting kids ready for school in India. · dosteducation.com | still up |
| 2015-01-01 | YCYhat End-to-end data science lifecycle management platform. · yhat.com | acquired |
| 2011-01-01 | Turning PhDs & engineers into data scientists & data engineers · insightdatascience.com | gone |
| 2025-06-01 | Optimizing fleet planning with data driven algorithms · fleetline.ai | still up |
| 2018-06-01 | Cancer Diagnosis 10X faster, 10X cheaper · datadrivenbioscience.com | still up |
| 2024-06-01 | VMware for GPUs · thundercompute.com | still up |
| 2023-06-01 | AI-powered insurance verification to boost patient conversion. · soharhealth.com | still up |
| 2023-06-01 | Transform scientific data into discoveries · mantlebio.com | gone |
| 2020-06-01 | YCBasedash The AI-native business intelligence platform · basedash.com | still up |
| 2024-06-01 | Powerful quantitative forecasting models · zoaresearch.com | still up |
| 2025-01-01 | Navigate any set of data - no matter how large - in minutes. · overstandlabs.com | still up |
| 2023-01-01 | YCNeptyne The programmable spreadsheet. · neptyne.com | gone |
| 2024-01-01 | YCcamelAI Unlimited inference at $5 per stream · camelai.com | still up |
| 2022-01-01 | YCCellbyte AI Agents for Pharma Drug Launches · cellbyte.com | still up |
| 2026-06-01 | Reliable and safe data engineering and data science agents · alkera.ai | still up |
| 2024-06-01 | YCMica AI Replace the humans fixing bad data · usemica.com | still up |
| 2024-06-01 | YCSharpe Agents for quantitative research and financial data science. · sharpe.sh | still up |
| 2023-06-01 | AI back office for food product quality teams · cognitioiq.com | still up |
| 2026-09-01 | YCQokedas Data for AI Science · qokedas.com | still up |
| 2026-06-01 | AI-native materials discovery powered by unpublished experimental data · 83sciences.ai | still up |
| 2020-06-01 | YCMito Cursor for data analysis · trymito.io | still up |
| 2026-06-01 | YCCueBench RL post-training for science reasoning and performance engineering · cuebench.dev | still up |
| 2026-06-01 | APIs for robotics data teams to verify data quality for model training · hebbianrobotics.com | still up |
| 2024-06-01 | YCMinusX Open source agentic BI for founders · minusx.ai | still up |
| 2026-06-01 | YCLyon Foundation models on enterprise transaction data. · lyon.so | still up |
| 2025-06-01 | YCLotas AI for quantitative trading · lotas.ai | still up |
| 2021-06-01 | YCPatterns Next-Gen Financial Analysis and Reporting with AI Agents · patterns.app | gone |
| 2024-01-01 | YCPreloop Translate your experimental scripts into production ML services · preloop.com | gone |
| 2024-01-01 | YCQuary The first in-browser analytics engineering platform · quary.dev | gone |
| 2024-01-01 | YCMetofico No Code Data Analysis for Life Science Research · metofico.com | still up |
| 2023-06-01 | YCBriefer The collaborative data platform. · briefer.cloud | gone |
| 2023-06-01 | YCVizly Data to insights in seconds · vizly.fyi | gone |
| 2015-06-01 | YCLeada Online enterprise training in data science and analytics.… · teamleada.com | gone |
| 2019-06-01 | YCDeepnote A better data science notebook. · deepnote.com | still up |
| 2013-01-01 | YCFivetran The leader in automated data movement · fivetran.com | still up |
| 2012-01-01 | Digital Analytics Platform · amplitude.com | acquired |
| 2012-06-01 | Unlocking the power of biotech with modern software for modern science · benchling.com | still up |
| 2011-06-01 | YCSegment Software and APIs to collect, clean, and control customer data. · segment.com | acquired |
| 2016-06-01 | YCScale AI Data-centric infrastructure to accelerate the development of AI · scale.com | still up |
| 2022-01-01 | Data driven neobank for SMBs in LATAM · kapital.mx | still up |
| 2009-06-01 | YCMixpanel Mixpanel is event analytics for builders that need answers. · mixpanel.com | still up |
| 2019-06-01 | YCTRM Labs TRM is building a safer world for billions of people. · trmlabs.com | still up |
| 2016-01-01 | AI + Robotics for the Built World · geckorobotics.com | still up |
| 2013-01-01 | The platform for building and operating time series applications. · influxdata.com | still up |
| 2014-06-01 | Rebuilding data in advertising to protect privacy · permutive.com | still up |
| 2019-06-01 | YCProlific Making diverse, high-quality data easily available to anyone, anywhere · prolific.com | still up |
| 2015-01-01 | YCMezmo Observability platform to control all of your log data · mezmo.com | still up |
| 2021-01-01 | YCEncord The data layer for physical AI · encord.com | still up |
| 2011-01-01 | The cloud-native, operational database built for speed and scale. · singlestore.com | still up |
| 2019-06-01 | Customer data collection, safeguarding, & activation for healthcare · freshpaint.io | still up |
| 2020-06-01 | YCSupabase Build in a weekend. Scale to millions. · supabase.com | still up |
| 2017-01-01 | YCNanoNets Automatic Data Extraction · nanonets.com | still up |
| 2011-06-01 | YCQuartzy Marketplace for life science supplies. · quartzy.com | still up |
| 2026-01-01 | Physical AI data lab · humanarchive.ai | still up |
| 2017-06-01 | Health enterprise API for data on doctors, insurance, costs, & quality · ribbonhealth.com | acquired |
| 2020-01-01 | YCAirbyte Context layer for production-grade AI agents · airbyte.com | still up |
How this compares
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.