You asked about Biotechnology
23 people built something like it. 2 are gone.
That is 9% of the ones whose fate we could settle, against 23% across the whole register. 1 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2017-01-01 | YCSolugen Decarbonizing the chemicals industry. · solugen.com | still up |
| 2016-01-01 | YCLygos Lygos engineers yeast to convert sugar into high-value industrial… · lygos.com | still up |
| 2020-01-01 | Foundation models and autonomous chambers for plant biology · urbankisaan.com | still up |
| 2019-01-01 | Unlocking the utility of genomics for the world. · voltalabs.com | still up |
| 2018-06-01 | YCMytos Robotic human cell manufacturing · mytos.bio | still up |
| 2021-06-01 | Unlocking the next generation of mRNA medicines · sensible.bio | still up |
| 2021-06-01 | Diversifying precision cancer diagnostics and treatments · yemaachi.com | still up |
| 2020-06-01 | Gilgamesh Pharmaceuticals, a Clinical stage biotechnology company… · gilgameshpharmaceutical.com | still up |
| 2017-06-01 | Rev is a biotechnology company creating better plants. · revgenomics.com | still up |
| 2020-01-01 | We’re creating programmable therapies · felixbt.com | gone |
| 2021-06-01 | Regulating the immune system to block cancer & autoimmune diseases · sfatherapeutics.com | still up |
| 2026-09-01 | Embodied Scientific Intelligence · superradiant.co | still up |
| 2026-06-01 | AI-native pharma company · atlasdiscovery.bio | still up |
| 2025-06-01 | Implantable microchips and AI for cattle monitoring · nexa.farm | acquired |
| 2026-01-01 | YCRitivel AI-native platform for Life-Sciences Documentation · ritivel.com | still up |
| 2024-06-01 | Making Next-Generation Antibiotics that Outpace Bacterial Evolution · evolverebiosciences.com | still up |
| 2017-01-01 | Sigma Genetics is a biotechnology company that is building… · sigmagenetics.com | still up |
| 2022-06-01 | Enabling Tissue Targeting of Therapies · eugittx.com | still up |
| 2014-06-01 | We enable cheaper, faster, and better genetic engineering of plants.… · taxa.com | gone |
| 2025-09-01 | YCScoop Automating regulatory submissions for life sciences · scooplabs.ai | still up |
| 2025-01-01 | A Disease Focused Biotech, Building Multiple Billion Dollar Drugs · uncommontherapeutics.com | still up |
| 2022-01-01 | YCAlixia Targeting the Tumor Ecosystem to address cancer drug resistance. · alixia.com | still up |
| 2026-06-01 | YCTareBio Vaccines for any cancer or infection in weeks. · tarebio.com | still up |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.