You asked about Anti-Aging
104 people built something like it. 31 are gone.
That is 36% of the ones whose fate we could settle, against 23% across the whole register. 17 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2017-06-01 | We bank your stem cells to help you live healthier, longer. · foreverlabs.com | still up |
| 2018-06-01 | New therapeutics to rejuvenate tissue and treat age-related diseases · doriantherapeutics.com | acquired |
| 2021-06-01 | Regulating the immune system to block cancer & autoimmune diseases · sfatherapeutics.com | still up |
| 2018-06-01 | YCdNovo The cure for hair loss. · dnovobio.com | gone |
| 2018-06-01 | mRNA therapeutics to extend healthspan entering clinical trials · rejuvenationtech.com | still up |
| 2012-06-01 | YCVoiceGem Voice messaging platform - Acquired by Palantir in 2013 · voicegem.com | acquired |
| 2021-01-01 | Longevity Nutrition Service · eatblueprint.com | gone |
| 2021-01-01 | YCLygg Building New Anti-Aging Ingredients for Skincare · lyggcorp.com | still up |
| 2016-06-01 | YCBird The world’s largest omnichannel communications platform · bird.com | still up |
| 2011-06-01 | Engage customers through personalized omni-channel messaging · onesignal.com | still up |
| 2019-01-01 | The phone that gives families peace of mind about aging parents · communityphone.org | still up |
| 2015-01-01 | YCLumi Packaging for online brands. · lumi.com | acquired |
| 2016-01-01 | YCChatfuel Platform to easily create chatbots to engage with audiences on… · chatfuel.com | still up |
| 2022-06-01 | YCBoostly Premier growth platform for restaurants · boostly.com | still up |
| 2020-01-01 | YCSINAI Enterprise software to quantify cost-effective decarbonization… · sinai.com | still up |
| 2021-01-01 | Plaid for Southeast Asia · finantier.co | gone |
| 2020-01-01 | YCTaiv AI-powered tech that makes business TV smarter, engaging, and… · taiv.tv | still up |
| 2019-06-01 | We help companies scale marketing campaigns through WhatsApp · treble.ai | still up |
| 2019-06-01 | YCCourier The fastest way for developers to build notifications for their app. · courier.com | still up |
| 2016-01-01 | All-In-One Business Operating System by PocketSuite · pocketsuite.io | still up |
| 2013-01-01 | Data and AI platform for Ecommerce & Cross-Border Logistics · semantics3.com | acquired |
| 2020-01-01 | Automated tooth cutting for dentists using imaging, AI and robotics · perceptive.io | still up |
| 2021-06-01 | YCBolster The platform for buying, selling and managing residential construction · bolsterbuilt.com | still up |
| 2020-06-01 | YCLaylo The CRM powering iconic musicians and events · laylo.com | still up |
| 2009-01-01 | YCVolantio Post-booking revenue and capacity optimization for airlines… · volantio.com | still up |
| 2016-01-01 | YCMailTime Emails as quick and easy as text messaging. · mailtime.com | still up |
| 2021-06-01 | YCUnion54 Developers of ChitChat, an integrated messaging and payments wallet… · union54.com | still up |
| 2022-06-01 | Managing your Employees' Access to SaaS · accessowl.io | still up |
| 2021-06-01 | Moving Things Around in Space, Imaging Space Objects When We're Not · turionspace.com | still up |
| 2021-01-01 | Discovering bispecific antibody drug-conjugates (BsADC) against cancer · valinktx.com | still up |
| 2017-01-01 | YCFibo SaaS calendar and messaging for SMBs · fiboapp.com | gone |
| 2016-01-01 | Carbon neutral packaging for ambitious businesses. · georgettepackaging.com | gone |
| 2018-01-01 | Computational antibody design · macromoltek.com | still up |
| 2020-01-01 | We create activating antibodies to treat diseases others can’t. · abalonebio.com | still up |
| 2018-01-01 | YCOpenland Messenger for communities · openland.com | gone |
| 2016-01-01 | YCmRelief mRelief has built an easy-to-use platform and web and text messaging… · mrelief.com | still up |
| 2016-01-01 | YCMio Mio powers seamless communication between workplace chat apps. · m.io | still up |
| 2022-01-01 | YCWingback Wingback provides tools and APIs for SaaS pricing and packaging. · wingback.com | gone |
| 2017-01-01 | YCArthena Quantitative Investment in Art Assets · arthena.com | acquired |
| 2014-01-01 | Message without interrupting what you're doing · hoverchat.com | gone |
| 2012-01-01 | YCMedigram We are making a HIPAA-compliant, Groupme app for doctors to… · medigram.com | still up |
| 2013-06-01 | YCHum A chat program that integrates with email, with presence. · letshum.com | gone |
| 2015-06-01 | YCLocent Locent is an automated messaging platform for companies · locent.com | gone |
| 2018-01-01 | Unified, enterprise messaging platform for leading brands of the world · glowing.io | still up |
| 2010-01-01 | Connecting users with engaging video content across the web.… · 140fire.com | acquired |
| 2018-06-01 | YCLowkey Capture, create, & share gaming moments (Acquired by Niantic!) · lowkey.gg | acquired |
| 2022-06-01 | Uncover high-fit leads already silently engaging with your brand · customeros.ai | gone |
| 2021-01-01 | YCPipeBio PipeBio is a SaaS bioinformatics platform to develop antibody drugs. · pipebio.com | acquired |
| 2020-06-01 | YCHere Where friends watch, play and hang together in digital rooms · here.fm | gone |
| 2021-01-01 | YCPingPong Video messaging app for remote teams. · getpingpong.com | acquired |
| 2021-01-01 | Analyzing EHR and messaging data to predict disease before it occurs. · quadrant.health | still up |
| 2020-06-01 | We use AI to design antibodies for intractable diseases · nabla.bio | still up |
| 2022-01-01 | YCLizza AI-assitant for managing creator-brand partnerships · lizza.link | still up |
| 2018-06-01 | Developing novel therapeutics for aging and chronic disease · gerostatealpha.com | gone |
| 2020-01-01 | YCEnveloop Design and send messages from your app with a simple API. · enveloop.com | gone |
| 2025-09-01 | YCMoss Real-time semantic search for Conversational AI · moss.dev | still up |
| 2021-06-01 | One-hour antibiotic sensitivity testing · astekdx.com | still up |
| 2021-06-01 | YCHilos Close and activate your customers on WhatsApp · hilos.io | acquired |
| 2020-01-01 | YCOpenUnit Software for managing self-storage facilities. · openunit.com | still up |
| 2018-06-01 | New clinical tests for managing autoimmune treatments. · coralgenomics.com | acquired |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.