You asked about AI-powered Drug Discovery
733 people built something like it. 113 are gone.
That is 16% of the ones whose fate we could settle, against 23% across the whole register. 16 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2022-01-01 | Growing micro-organs to find new drugs · rosebudbiosciences.com | still up |
| 2022-06-01 | YCKeylika Redefining the Standard of Care for Iron Deficiency Anemia · keylika.com | still up |
| 2022-01-01 | Unleashing the potential of DNA and RNA based therapies using AI · whitelabgx.com | still up |
| 2022-06-01 | YCQuinn Your biopharma team, from molecule design to portfolio strategy · quinnbio.com | still up |
| 2022-06-15 | softr.io | still up |
| 2022-05-05 | supermeme.ai | still up |
| 2022-10-17 | lex.page | still up |
| 2022-11-13 | podcast.adobe.com | still up |
| 2022-10-03 | exactbuyer.com | gone |
| 2022-11-18 | freesubtitles.ai | moved |
| 2022-10-27 | whatthediff.ai | still up |
| 2022-04-04 | hirequotient.com | still up |
| 2022-01-31 | ideas-generator.com | gone |
| 2022-05-19 | depositphotos.com | still up |
| 2022-01-19 | dubverse.ai | still up |
| 2022-07-22 | faceswapper.ai | still up |
| 2022-02-09 | substrata.me | unverified |
| 2022-10-27 | speechanalyzer.elsaspeak.com | still up |
| 2022-04-28 | visily.ai | still up |
| 2022-01-04 | huski.ai | still up |
| 2022-05-31 | classtra.org | still up |
| 2022-10-31 | airbrush.ai | still up |
| 2022-05-24 | meetclockwork.com | unverified |
| 2022-04-29 | tradeswell.com | moved |
| 2022-07-12 | pixieapp.co | still up |
| 2022-01-01 | YCRDash AI Powered Construction Management Software · rdash.io | still up |
| 2022-09-08 | tattoosai.com | still up |
| 2022-06-01 | YCJuicebox AI-powered talent sourcing for recruiters · juicebox.ai | still up |
| 2022-06-01 | YCAiPrise AI-powered Global Compliance Platform · aiprise.com | still up |
| 2022-01-01 | YCUnlayer AI-powered content creation infrastructure for apps · unlayer.com | still up |
| 2022-12-04 | remarkai.in | gone |
| 2022-01-01 | YCCuracel AI-Powered Infrastructure for Insurance & Healthcare · curacel.co | still up |
| 2022-01-01 | YCFinku AI powered personal finance app for Indonesia · finku.id | still up |
| 2022-01-01 | YCSekilo Building the AI powered halal protein supply chain for foodservice in… · sekilo.com | still up |
| 2022-07-04 | loom.com | still up |
| 2022-01-01 | YCLumina AI+human powered automation on job-community platform with 1.5M… · lumibot.com | still up |
| 2022-01-01 | Potent, durable, and redosable non-viral genetic medicines · engagebio.com | acquired |
| 2022-01-01 | YCArgo A social streaming platform powered by creators and fans · argo.la | still up |
| 2022-01-01 | YCPeakPath Smartwatch powered coaching to improve teams sustainable performance · peakpath.com | gone |
| 2022-06-01 | AI-powered business matchmaking · namecard.ai | still up |
| 2022-01-01 | YCStrac Data Discovery, DLP, DSPM for SaaS, Cloud, Gen AI & Endpoints · strac.io | still up |
| 2022-01-01 | YCSphere AI-powered sales tax, VAT and GST compliance · getsphere.com | still up |
| 2022-12-19 | giftgenie.ai | still up |
| 2022-01-01 | AI-powered scalable infrastructure + mental health services, starting… · hellolunajoy.com | still up |
| 2022-01-01 | Vision-powered warehouse automation: maximizing performance and value · powerhouseai.com | still up |
| 2022-06-01 | YCCapix AI-powered private equity intelligence. · capix.ai | still up |
| 2022-01-01 | YCCoffeeAI Instant, hyper-personalized, AI-powered outreach messages · get-coffee.ai | gone |
| 2022-12-14 | aispiritanimal.com | gone |
| 2022-11-25 | meepo.shop | still up |
| 2022-06-01 | Platform injectable gel based therapeutic for osteoarthritis · relevium-medical.com | still up |
| 2022-01-01 | Oral drugs to halt neurodegeneration · origamitherapeutics.com | still up |
| 2022-06-01 | API for Retrieval Augmented Generation · superpowered.ai | gone |
| 2022-06-01 | YCStellar AI-powered business goals · stellarapp.io | gone |
| 2022-01-01 | YCCellbyte AI Agents for Pharma Drug Launches · cellbyte.com | still up |
| 2022-01-01 | YCVersable AI powered product description enhancement for the auto parts industry · versableai.com | still up |
| 2022-01-01 | Bioinformatics pipelines in the cloud · flowdeploy.com | gone |
| 2022-06-01 | YCFlatX AI-Powered Rental Platform for Urban Renters · flatx.co | still up |
| 2022-06-01 | YCElessar AI-powered engineering productivity tools · getelessar.com | still up |
| 2022-01-01 | YCAlixia Targeting the Tumor Ecosystem to address cancer drug resistance. · alixia.com | still up |
| 2022-06-01 | AI powered web & mobile automation · dev-tools.ai | gone |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.