You asked about AI-powered Drug Discovery
157 people built something like it. 60 are gone.
That is 38% of the ones whose fate we could settle, against 23% across the whole register. Half of the gone ones were last seen within 20 months of launching.
| Launched | What it was | Today |
|---|---|---|
| 2021-03-16 | about.cryptotask.org | still up |
| 2021-01-03 | headlime.com | still up |
| 2021-09-03 | examples.jina.ai | gone |
| 2021-02-04 | evertrove.co | unverified |
| 2021-12-15 | explaincode.app | still up |
| 2021-05-01 | namebatao.com | gone |
| 2021-06-24 | reviewr.ai | still up |
| 2021-06-01 | wordblot.ai | gone |
| 2021-07-14 | booklyn.co | unverified |
| 2021-09-30 | tangle.work | unverified |
| 2021-07-12 | obsidian.md | still up |
| 2021-04-01 | mailstudio.app | still up |
| 2021-12-29 | a9.io | still up |
| 2021-01-23 | rysolv.com | moved |
| 2021-06-12 | landrop.app | still up |
| 2021-08-18 | pop.com | still up |
| 2021-05-28 | ninfex.com | unverified |
| 2021-06-26 | cq.mtc.dev | gone |
| 2021-10-03 | spotml.io | gone |
| 2021-08-24 | easyzoom.com | still up |
| 2021-03-31 | threethingsdaily.xyz | gone |
| 2021-01-11 | thumbnail.ai | unverified |
| 2021-04-22 | app.litmaps.co | moved |
| 2021-01-15 | forgojs.org | still up |
| 2021-07-27 | photoroom.com | still up |
| 2021-09-17 | ish.im | unverified |
| 2021-09-24 | gocoder.one | still up |
| 2021-09-17 | forlater.email | still up |
| 2021-04-18 | aidmin.io | still up |
| 2021-08-18 | tangram.dev | still up |
| 2021-02-03 | pairagraph.com | still up |
| 2021-07-18 | muler.pythonanywhere.com | unverified |
| 2021-12-28 | mlconsole.com | still up |
| 2021-06-22 | companydirectory.uk | gone |
| 2021-01-22 | blocks.wickedtemplates.com | moved |
| 2021-11-07 | hewellapp.com | unverified |
| 2021-05-25 | sendsimple.app | still up |
| 2021-09-17 | flowbite.com | still up |
| 2021-08-29 | voicera.co | still up |
| 2021-01-23 | traindown.com | still up |
| 2021-06-29 | blog.framelabs.eu | unverified |
| 2021-09-10 | finlo.io | unverified |
| 2021-06-25 | sirendns.com | gone |
| 2021-04-15 | offsideornot.com | still up |
| 2021-02-01 | subaligner.readthedocs.io | still up |
| 2021-09-28 | pixeldrain.com | still up |
| 2021-05-27 | wndr.xyz | unverified |
| 2021-03-12 | neonpad.io | moved |
| 2021-07-12 | silverdial.org | gone |
| 2021-10-02 | airss.roastidio.us | still up |
| 2021-07-30 | volantai.org | gone |
| 2021-10-06 | peersend.com | gone |
| 2021-04-09 | exportoutlookmacmail.com | still up |
| 2021-09-28 | exafunction.com | unverified |
| 2021-09-23 | logtail.com | moved |
| 2021-10-13 | shademap.app | still up |
| 2021-07-22 | readow.ai | still up |
| 2021-12-21 | joeldare.com | still up |
| 2021-04-05 | ampie.app | still up |
| 2021-03-19 | drovio.com | still up |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.