You asked about Drug discovery
11 people built something like it. 11 are gone.
That is 100% of the ones whose fate we could settle, against 23% across the whole register.
| Launched | What it was | Today |
|---|---|---|
| 2018-01-01 | Engineering next-generation, brain-penetrant cancer therapies. · reverielabs.com | gone |
| 2019-01-01 | We solve drug resistance for cancer · resistance.bio | gone |
| 2010-06-01 | YCTeevox Teevox · teevox.com | gone |
| 2020-01-01 | We’re creating programmable therapies · felixbt.com | gone |
| 2021-01-01 | Discover drugs that control how much cells "squeeze" to treat disease · forcytebio.com | gone |
| 2019-06-01 | EncepHeal develops medications to treat substance abuse, starting… · encepheal.com | gone |
| 2022-01-01 | Bioinformatics pipelines in the cloud · flowdeploy.com | gone |
| 2023-01-01 | AI for drug formulation · lavo.ai | gone |
| 2020-06-01 | Accelerating protein engineering. · trident.bio | gone |
| 2023-01-01 | AI Powered Product Discovery · rubberduckylabs.io | gone |
| 2017-06-01 | Caelum Health is replacing drugs with software. We use behavioral… · caelumhealth.com | gone |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.