You asked about Biotech
16 people built something like it. 16 are gone.
That is 100% of the ones whose fate we could settle, against 23% across the whole register.
| Launched | What it was | Today |
|---|---|---|
| 2018-01-01 | Engineering next-generation, brain-penetrant cancer therapies. · reverielabs.com | gone |
| 2016-01-01 | YCUnima Fast and low-cost diagnostics for real time disease surveillance · unimadx.com | gone |
| 2018-01-01 | YCOvipost Automated insect farming · ovipost.com | gone |
| 2015-01-01 | The robotic cloud laboratory for the life sciences. · transcriptic.com | gone |
| 2017-01-01 | YCInnaMed At-home blood testing: measure + analyze + enhance. · innamed.com | gone |
| 2018-06-01 | Operating systems for biology labs · radix.bio | gone |
| 2023-06-01 | Transform scientific data into discoveries · mantlebio.com | gone |
| 2018-06-01 | Developing novel therapeutics for aging and chronic disease · gerostatealpha.com | gone |
| 2020-01-01 | We’re creating programmable therapies · felixbt.com | gone |
| 2021-01-01 | Discover drugs that control how much cells "squeeze" to treat disease · forcytebio.com | gone |
| 2023-01-01 | AI for drug formulation · lavo.ai | gone |
| 2015-01-01 | YC20n Using AI to predict biochemistry for manufacturing and therapeutics · 20n.com | gone |
| 2018-06-01 | Democratizing gene therapy by reinventing its manufacturing and… · perception.bio | gone |
| 2014-06-01 | We enable cheaper, faster, and better genetic engineering of plants.… · taxa.com | gone |
| 2024-06-01 | AI document creation and data management for clinical trials · baselinetrials.com | gone |
| 2021-06-01 | Technologies for scaling up cultured/clean meat production · micromeat.com | gone |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.