You asked about IoT
25 people built something like it. 0 are gone.
That is 0% of the ones whose fate we could settle, against 23% across the whole register.
| Launched | What it was | Today |
|---|---|---|
| 2021-01-01 | YCTractian Physical AI for asset-heavy industries · tractian.com | still up |
| 2021-01-01 | YCgaiia all-in-one operating system (OS) for telcos · gaiia.com | still up |
| 2021-01-01 | Robots that automate the everyday tasks of microbiologists. · reshapebiotech.com | still up |
| 2021-06-01 | Unlocking the next generation of mRNA medicines · sensible.bio | still up |
| 2021-06-01 | Using the immune system to cure disease · parallel.bio | still up |
| 2021-06-01 | Diversifying precision cancer diagnostics and treatments · yemaachi.com | still up |
| 2021-06-01 | Discovering drugs that target the DNA regulome · talus.bio | still up |
| 2021-06-01 | YCScispot The Best Data Infrastructure for Biotechs · scispot.io | still up |
| 2021-01-01 | Discovering bispecific antibody drug-conjugates (BsADC) against cancer · valinktx.com | still up |
| 2021-06-01 | We help nurses in nursing homes to be 30% more effective · momomedical.com | still up |
| 2021-06-01 | Patent-pending enzymes to break down common dietary triggers · fodzyme.com | still up |
| 2021-01-01 | GreaseBoss verifes industrial machinery is greased correctly · greaseboss.com.au | still up |
| 2021-06-01 | We make injections as easy as pushing a button! · pirouettepharma.com | still up |
| 2021-06-01 | YCEpinoma We engineer proteins that control the operating system of biology. · epinoma.com | still up |
| 2021-06-01 | The foundation for the next era of biology · outputbio.com | still up |
| 2021-06-01 | Multi-targeted therapeutics to treat complex diseases · harmonicdiscovery.com | still up |
| 2021-06-01 | Programmable biology company for psychoactive effect design · mindstate.design | still up |
| 2021-06-01 | Using protein coupling to build new therapies · catenabiosciences.com | still up |
| 2021-06-01 | AI-designed Affinity Reagents · medium.bio | still up |
| 2021-01-01 | Genetic Medicine with Small Molecules · serna.bio | still up |
| 2021-06-01 | One-hour antibiotic sensitivity testing · astekdx.com | still up |
| 2021-06-01 | YCBLUUMBIO We make bacteria and plants that clean up pollution. · bluumbio.com | still up |
| 2021-06-01 | Regulating the immune system to block cancer & autoimmune diseases · sfatherapeutics.com | still up |
| 2021-01-01 | Creating a New Class of Drugs to Address Incurable Autoimmune Diseases · entelexo.com | still up |
| 2021-01-01 | Bioengineered kidneys for patients with kidney failure · trestlebio.com | still up |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.