You asked about Genetic Engineering
26 people built something like it. 5 are gone.
That is 28% of the ones whose fate we could settle, against 23% across the whole register. 8 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2014-01-01 | YCAlgolia A developer-friendly and enterprise-grade search API. · algolia.com | still up |
| 2020-06-01 | YCDecentro API Platform for Banking Integrations (Plaid for India and APAC) · decentro.tech | still up |
| 2021-01-01 | YCMindee AI Document Understanding API · mindee.com | still up |
| 2011-01-01 | YCMailgun Email API service. · mailgun.net | acquired |
| 2023-01-01 | YCFern Instantly offer SDKs and API Docs · buildwithfern.com | acquired |
| 2020-06-01 | YCSeam API for IoT Devices · seam.co | still up |
| 2021-01-01 | API for developers and AIs to access health data · tryterra.co | still up |
| 2022-01-01 | YCTheneo Stripe-like API Docs in just a few clicks · theneo.io | still up |
| 2019-06-01 | YCRutter The Unified API for Business Financial Data · rutter.com | still up |
| 2014-01-01 | YCWit.ai Natural Language for Developers --Wit is an API that makes it easy… · wit.ai | acquired |
| 2020-01-01 | YCWeav Weav is the universal API for commerce platforms · weav.co | acquired |
| 2023-01-01 | YCNango A single API for all your integrations · nango.dev | still up |
| 2020-01-01 | YCEnveloop Design and send messages from your app with a simple API. · enveloop.com | gone |
| 2024-01-01 | API For PDF Document Workflows · fileforge.com | gone |
| 2022-01-01 | API for shared embeddable web browsers · hyperbeam.com | still up |
| 2019-06-01 | Turn any website into an API · dashblock.com | gone |
| 2023-06-01 | The API for LLM tool use · opentools.com | still up |
| 2022-01-01 | Open-source API & UI test automation · karatelabs.io | still up |
| 2025-01-01 | YCReJot We turn complex API integrations into drop‑in full‑stack libraries · rejot.dev | still up |
| 2018-06-01 | YCOneGraph GraphQL API to connect all of the internet's APIs. Join us at Netlify! · onegraph.com | acquired |
| 2019-01-01 | YCBasilica Basilica is an API that embeds high-dimensional data like images and… · basilica.ai | gone |
| 2018-01-01 | YCNewCraft Universal API for HR & Payroll · newcraft.io | acquired |
| 2017-01-01 | The Universal API · scaphold.io | acquired |
| 2019-06-01 | YCBouncer SDK for scanning and verifying credit cards and photo IDs in mobile… · getbouncer.com | acquired |
| 2024-06-01 | YCPinnacle API & SDK for RCS (the next-generation of texting) · pinnacle.sh | still up |
| 2022-01-01 | YCSendo The best SMS/RCS API for startups · sendo.dev | gone |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.