You asked about Live
32 people built something like it. 2 are gone.
That is 6% of the ones whose fate we could settle, against 23% across the whole register. 1 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2021-01-01 | YCLiveFlow The Unified AI-ERP & FP&A Platform · liveflow.com | still up |
| 2015-06-01 | We use human data and AI to develop better drugs faster. · vergegenomics.com | still up |
| 2022-01-01 | Unleashing the potential of DNA and RNA based therapies using AI · whitelabgx.com | still up |
| 2014-01-01 | YCMixerBox AI Super-Apps to Live Easier | The anything anytime superapps… · mixerbox.com | still up |
| 2019-06-01 | Arpeggio Bio develops drugs targeting transcription factors using AI… · arpeggiobio.com | still up |
| 2020-06-01 | AI-native Robotics · nexterarobotics.com | still up |
| 2021-06-01 | Security Delivery Platform to orchestrate AI agents for Service… · contraforce.com | still up |
| 2023-01-01 | Generative AI for protein design · diffuse.bio | still up |
| 2016-06-01 | An AI-powered digital grocer that delivers in under 60 mins. · farmsteadapp.com | gone |
| 2020-06-01 | We use AI to design antibodies for intractable diseases · nabla.bio | still up |
| 2026-06-01 | YCDonkey The AI-native trading company: factory prices, delivered, one number · donkey.trade | still up |
| 2022-06-01 | Manufacturing more proteins with AI. · tenlives.com | still up |
| 2023-01-01 | Developing long-lasting drug formulations 50% faster · persist-ai.com | still up |
| 2023-06-01 | YCNanograb Deliver genes to any cell with AI · nanograb.com | still up |
| 2023-06-01 | YCCedana Fast, reliable, reproducible AI with GPU live migration · cedana.ai | still up |
| 2024-06-01 | Gen AI molecular simulations that reproduce wetlab results · angstrom-ai.com | still up |
| 2025-09-01 | YCCaddy Your Personal AI for everyday work. Lives in your texts. · caddy.app | still up |
| 2025-06-01 | Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF. · roboticscenter.ai | still up |
| 2026-01-01 | YCOrigin AI and Data for Cancer Therapeutics · origin.bio | still up |
| 2025-06-01 | YCConvexia The world's first AI-maximalist pharma company · convexia.bio | still up |
| 2025-09-01 | YCExonic Exonic is an AI-native cell and gene therapeutics company. · exonic.ai | still up |
| 2025-01-01 | YCPinch AI Voice Translation for live conversations or media · startpinch.com | still up |
| 2024-01-01 | YCkater.ai Deliver complete data analysis from a single question · kater.ai | still up |
| 2026-09-01 | AI spacecraft operators that lives onboard the vehicle · orcaaerospace.com | still up |
| 2023-01-01 | AI for drug formulation · lavo.ai | gone |
| 2025-06-01 | Implantable microchips and AI for cattle monitoring · nexa.farm | acquired |
| 2026-06-01 | AI-native pharma company · atlasdiscovery.bio | still up |
| 2025-01-01 | YCOlive Build internal tools with AI · fromolive.com | still up |
| 2018-06-01 | Synkrino's AI, SATIS is a powerful, unbiased discovery system for… · synkrino.bio | still up |
| 2026-01-01 | Multimodal foundation models to predict uncollected patient biology · strandai.com | still up |
| 2020-01-01 | Menten AI designs peptide and protein therapeutics using quantum… · menten.ai | still up |
| 2025-09-01 | YCLakonia Delivering AI-powered situational awareness in tactical environments. · lakonia.us.com | still up |
How this compares
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.