You asked about Live
36 people built something like it. 2 are gone.
That is 6% of the ones whose fate we could settle, against 23% across the whole register. 1 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2022-05-31 | classtra.org | still up |
| 2022-03-15 | zipy.ai | still up |
| 2021-01-01 | YCLiveFlow The Unified AI-ERP & FP&A Platform · liveflow.com | still up |
| 2015-06-01 | We use human data and AI to develop better drugs faster. · vergegenomics.com | still up |
| 2022-01-01 | Unleashing the potential of DNA and RNA based therapies using AI · whitelabgx.com | still up |
| 2014-01-01 | YCMixerBox AI Super-Apps to Live Easier | The anything anytime superapps… · mixerbox.com | still up |
| 2019-06-01 | Arpeggio Bio develops drugs targeting transcription factors using AI… · arpeggiobio.com | still up |
| 2020-06-01 | AI-native Robotics · nexterarobotics.com | still up |
| 2021-06-01 | Security Delivery Platform to orchestrate AI agents for Service… · contraforce.com | still up |
| 2023-05-11 | earth.atmo.ai | still up |
| 2016-06-01 | An AI-powered digital grocer that delivers in under 60 mins. · farmsteadapp.com | gone |
| 2023-01-01 | Generative AI for protein design · diffuse.bio | still up |
| 2026-09-01 | videoai.me | unverified |
| 2020-06-01 | We use AI to design antibodies for intractable diseases · nabla.bio | still up |
| 2026-06-01 | YCDonkey The AI-native trading company: factory prices, delivered, one number · donkey.trade | still up |
| 2022-06-01 | Manufacturing more proteins with AI. · tenlives.com | still up |
| 2023-01-01 | Developing long-lasting drug formulations 50% faster · persist-ai.com | still up |
| 2024-06-01 | Gen AI molecular simulations that reproduce wetlab results · angstrom-ai.com | still up |
| 2021-10-15 | blogaudio.co | still up |
| 2026-08-18 | testflight.apple.com | unverified |
| 2025-09-01 | YCCaddy Your Personal AI for everyday work. Lives in your texts. · caddy.app | still up |
| 2023-06-01 | YCNanograb Deliver genes to any cell with AI · nanograb.com | still up |
| 2023-06-01 | YCCedana Fast, reliable, reproducible AI with GPU live migration · cedana.ai | still up |
| 2026-01-01 | YCOrigin AI and Data for Cancer Therapeutics · origin.bio | still up |
| 2025-06-01 | Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF. · roboticscenter.ai | still up |
| 2025-06-01 | YCConvexia The world's first AI-maximalist pharma company · convexia.bio | still up |
| 2025-09-01 | YCExonic Exonic is an AI-native cell and gene therapeutics company. · exonic.ai | still up |
| 2025-01-01 | YCPinch AI Voice Translation for live conversations or media · startpinch.com | still up |
| 2024-01-01 | YCkater.ai Deliver complete data analysis from a single question · kater.ai | still up |
| 2023-01-01 | AI for drug formulation · lavo.ai | gone |
| 2026-09-01 | AI spacecraft operators that lives onboard the vehicle · orcaaerospace.com | still up |
| 2025-06-01 | Implantable microchips and AI for cattle monitoring · nexa.farm | acquired |
| 2026-06-01 | AI-native pharma company · atlasdiscovery.bio | still up |
| 2025-01-01 | YCOlive Build internal tools with AI · fromolive.com | still up |
| 2025-09-01 | YCLakonia Delivering AI-powered situational awareness in tactical environments. · lakonia.us.com | still up |
| 2018-06-01 | Synkrino's AI, SATIS is a powerful, unbiased discovery system for… · synkrino.bio | still up |
| 2020-01-01 | Menten AI designs peptide and protein therapeutics using quantum… · menten.ai | still up |
| 2026-01-01 | Multimodal foundation models to predict uncollected patient biology · strandai.com | still up |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.