You asked about Industrial Bio
109 people built something like it. 5 are gone.
That is 5% of the ones whose fate we could settle, against 23% across the whole register. 5 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2023-01-01 | Gen-AI Designed Enzymes for Pharmaceutical Innovation · pando.bio | still up |
| 2025-06-01 | Implantable microchips and AI for cattle monitoring · nexa.farm | acquired |
| 2025-06-01 | AI infrastructure for biosecurity · twentytwo.bio | still up |
| 2015-01-01 | YC20n Using AI to predict biochemistry for manufacturing and therapeutics · 20n.com | gone |
| 2021-01-01 | YCTractian Physical AI for asset-heavy industries · tractian.com | still up |
| 2016-01-01 | AI + Robotics for the Built World · geckorobotics.com | still up |
| 2026-01-01 | Physical AI data lab · humanarchive.ai | still up |
| 2022-06-01 | YCCambio AI-native commercial real estate operations · cambio.ai | still up |
| 2021-01-01 | Physical AI for Warehouses and Factories · fluxauto.ai | still up |
| 2022-06-01 | YCPaces Agentic AI for Power Projects and AI Infrastructure · paces.com | still up |
| 2019-01-01 | YCOverview Reshaping industrial quality with AI, hardware, and software · overview.ai | still up |
| 2018-01-01 | Orangewood Labs makes worlds most affordable and easiest AI robot arms · orangewood.co | still up |
| 2026-06-01 | Mass-produced AI strike systems and Counter-UAS · isengardindustries.com | still up |
| 2022-01-01 | YCKorrAI Traceable AI for billion-dollar infrastructure. · korrai.com | still up |
| 2024-01-01 | AI Inference Platform for Drug Discovery · tamarind.bio | still up |
| 2020-06-01 | AI-native Robotics · nexterarobotics.com | still up |
| 2020-01-01 | YCPowerX AI powered sensors that save energy, water and emissions · powerx.co | acquired |
| 2019-06-01 | Arpeggio Bio develops drugs targeting transcription factors using AI… · arpeggiobio.com | still up |
| 2022-06-01 | YCCerrion Video AI to automatically detect and respond to production line… · cerrion.com | still up |
| 2021-06-01 | YCFerveret Nuclear-inspired cooling that turns wasted power into more AI compute · ferveret.com | still up |
| 2025-01-01 | YCConntour AI to monitor thousands of security cameras. · conntour.com | still up |
| 2025-01-01 | AI powered operating system for distributors and OEMs · salespatriot.com | still up |
| 2025-01-01 | YCBindwell Discovering new pesticides with AI · bindwell.ai | still up |
| 2019-06-01 | YCEARTH AI Predictive Explorer and Driller for Critical Metal Deposits · earth-ai.com | still up |
| 2018-06-01 | YCPhiar We are developing a revolutionary AI-powered augmented reality… · phiar.net | acquired |
| 2024-06-01 | YCDistro The AI co-pilot for sales reps at industrial wholesale distributors. · distro.app | still up |
| 2022-06-01 | YCLamin Open data platform for traceable, multimodal AI · lamin.ai | still up |
| 2023-01-01 | Generative AI for protein design · diffuse.bio | still up |
| 2020-01-01 | YCAtmo Ultra-precise AI weather forecasting. · atmo.ai | still up |
| 2025-09-01 | YCMOVEdot AI Agents for Hardware Engineering · movedot.ai | still up |
| 2022-01-01 | IndustrialNext builds the AI brain for manufacturing –… · industrialnext.ai | still up |
| 2025-01-01 | AI drug discovery platform for neurotherapeutics · exintherapeutics.com | still up |
| 2021-01-01 | YCBiodock Cloud AI microscopy automation · biodock.ai | still up |
| 2020-06-01 | We use AI to design antibodies for intractable diseases · nabla.bio | still up |
| 2025-06-01 | AI models that teach robots new skills in hours · vernerobotics.com | still up |
| 2026-01-01 | Modular AI-Commanded Drones for Defence · seeing-systems.com | still up |
| 2024-01-01 | Agent-Driven Engineering · navier.ai | still up |
| 2023-06-01 | YCNectar Manage energy cost & usage with AI for facility & sustainability teams · nectarclimate.com | still up |
| 2024-01-01 | AI for Robot Arms in Factories · pivotrobotics.com | still up |
| 2025-06-01 | Build AI agents for field technicians to diagnose and sell 10x better · noso.so | still up |
| 2025-09-01 | YCAllus AI Transforming manufacturing with our next-gen Vision Foundation Model · allus.ai | still up |
| 2021-06-01 | AI-designed Affinity Reagents · medium.bio | still up |
| 2022-01-01 | YCHypaHub A Cloud-Based Bioinformatics and AI Platform · hypahub.com | acquired |
| 2026-09-01 | Robotics for AI Infrastructure · lambdarobotics.ai | still up |
| 2025-06-01 | YCNovaflow The AI data analyst for biology labs · novaflow.ai | still up |
| 2025-06-01 | YCAvent AI agents for industrial commerce · aventindustrial.com | still up |
| 2026-01-01 | The AI-native platform for next-generation protein characterization. · 10xscience.com | still up |
| 2020-01-01 | AI that tells mining companies where to mine to maximize profits · stratum.ai | still up |
| 2023-06-01 | YCNanograb Deliver genes to any cell with AI · nanograb.com | still up |
| 2018-06-01 | Software for robotaxi operations. · passenger.ai | gone |
| 2026-06-01 | YCMarengo AI-Native Engineering Firm designing Data Centers · marengox.com | still up |
| 2024-06-01 | Gen AI molecular simulations that reproduce wetlab results · angstrom-ai.com | still up |
| 2021-06-01 | Computer vision that makes the industrial workplace, safer · protex.ai | still up |
| 2024-06-01 | AI that operates quantum computers for scientific discovery · conductorquantum.com | still up |
| 2026-06-01 | AI that turns any camera to an autonomous worker with real-time vision · openvector.com | still up |
| 2026-01-01 | AI benchmarks that measure general intelligence and inspire new ideas · arcprize.org | still up |
| 2026-06-01 | YC6thSense Nervous System for Physical AI · 6thsense.dev | still up |
| 2026-06-01 | AI-native electronics manufacturing for the American industrial base · provenmetal.com | still up |
| 2025-06-01 | Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF. · roboticscenter.ai | still up |
| 2025-06-01 | YCConvexia The world's first AI-maximalist pharma company · convexia.bio | still up |
How this compares
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.