You asked about Gene Therapy
27 people built something like it. 6 are gone.
That is 23% of the ones whose fate we could settle, against 23% across the whole register. 1 were acquired.
| Launched | What it was | Today |
|---|---|---|
| 2021-08-24 | easyzoom.com | still up |
| 2021-01-01 | YCPibit.ai The fastest path from submission to better decisions. · pibit.ai | still up |
| 2021-01-01 | Building the next generation AI creative studio · moonvalley.com | still up |
| 2021-06-01 | YCTavus Building the human layer of AI · tavus.io | still up |
| 2021-06-01 | Track & Boost Your Brand’s Visibility in AI Search · writesonic.com | still up |
| 2021-01-01 | DreamWorld is a next-gen Minecraft with generative AI building · playdreamworld.com | still up |
| 2021-01-01 | Generative AI powered Shopify for home service professionals · toplinepro.com | still up |
| 2021-06-01 | The most magical personal Voice-Led AI English Learning Buddy for Kids · sparkstudio.co | still up |
| 2021-06-01 | The fastest way to ship airtight AI · openlayer.com | still up |
| 2021-01-01 | YCDatrics Generative AI Healthcare Coding Automation · datrics.ai | still up |
| 2021-06-01 | YCCoLoop AI Copilot for insights & strategy · coloop.ai | still up |
| 2021-01-01 | YCarnata AI workers for the logistics industry. · arnata.com | still up |
| 2021-06-01 | Affogato AI — Your Agent for instant TikToks, Reels, and ads. · affogato.ai | still up |
| 2021-06-01 | AI native mobile testing. · mobileboost.io | still up |
| 2021-01-07 | uniqueaiart.com | gone~35mo |
| 2021-06-01 | Plan and review AI generated code · vibekanban.com | still up |
| 2021-05-24 | teza.ai | still up |
| 2021-07-10 | canyouguess.art | gone |
| 2021-06-01 | YCPotion AI for product formulation · potion.ai | still up |
| 2021-12-01 | galeras.io | gone |
| 2021-06-01 | Tiktok for fashion - where designers show their work + build traction · revery.ai | gone |
| 2021-05-01 | namebatao.com | gone |
| 2021-09-15 | docstring.dev | gone |
| 2021-10-15 | blogaudio.co | still up |
| 2021-01-01 | YCAvocado AI-Native Restaurant POS · avocadopos.com | still up |
| 2021-06-01 | YCBytebot Bytebot is the open source container for AI desktop agents. · bytebot.ai | acquired |
| 2021-06-01 | YCSequin Sequin is building AI Voice Agents to automate collections calls for… · sequinai.com | still up |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.