You asked about AI-powered Drug Discovery
228 people built something like it. 228 are gone.
That is 100% of the ones whose fate we could settle, against 23% across the whole register.
| Launched | What it was | Today |
|---|---|---|
| 2023-01-01 | AI for drug formulation · lavo.ai | gone |
| 2023-01-01 | AI Powered Product Discovery · rubberduckylabs.io | gone |
| 2022-10-03 | exactbuyer.com | gone |
| 2022-01-31 | ideas-generator.com | gone |
| 2021-09-03 | examples.jina.ai | gone |
| 2022-12-04 | remarkai.in | gone |
| 2015-06-01 | ROSS is an AI-powered legal research platform that can read and… · rossintelligence.com | gone |
| 2023-08-08 | allclues.ai | gone |
| 2023-05-09 | flippit.ai | gone |
| 2023-09-25 | octomind.dev | gone |
| 2016-06-01 | An AI-powered digital grocer that delivers in under 60 mins. · farmsteadapp.com | gone |
| 2019-01-01 | AI-powered corporate learning for accelerated employee growth & skill… · tailor-ed.com | gone |
| 2023-02-07 | dbsensei.com | gone |
| 2023-06-29 | clevis.volca.io | gone |
| 2023-05-21 | planitearth.travel | gone |
| 2022-01-01 | YCCoffeeAI Instant, hyper-personalized, AI-powered outreach messages · get-coffee.ai | gone |
| 2021-05-01 | namebatao.com | gone |
| 2021-06-01 | wordblot.ai | gone |
| 2023-02-14 | vday.galerie.ai | gone |
| 2022-06-01 | API for Retrieval Augmented Generation · superpowered.ai | gone |
| 2023-01-01 | AI-powered customer support automation for fast-growing companies · opensight.ai | gone |
| 2022-06-01 | YCStellar AI-powered business goals · stellarapp.io | gone |
| 2019-01-01 | YCHypnos AI-powered sleep coach learns and optimizes your sleep · hypnos.ai | gone |
| 2021-01-01 | YCCodeball AI-Powered Code Review · codeball.ai | gone |
| 2024-01-01 | The world's best presentation editor, powered by AI. · thorntale.com | gone |
| 2022-06-01 | AI powered web & mobile automation · dev-tools.ai | gone |
| 2017-06-01 | First agentic AI-powered community for 1 billion people with criminal… · commissary.club | gone |
| 2024-01-01 | Your team’s AI powered communication tool · atpatchwork.com | gone |
| 2023-01-01 | AI-powered data extraction engine · indexical.dev | gone |
| 2022-08-23 | pornpen.ai | gone |
| 2022-11-30 | thegist.ai | gone |
| 2023-06-25 | dialup.net | gone |
| 2022-04-26 | sigmamail.ai | gone |
| 2023-02-22 | jotte.ai | gone |
| 2022-04-22 | sonero.ai | gone |
| 2023-04-12 | librarian-ai.com | gone |
| 2022-03-31 | lisnclips.app | gone |
| 2022-06-28 | snackable.ai | gone |
| 2022-01-05 | nonnfts.com | gone |
| 2022-04-14 | quicklines.ai | gone |
| 2022-12-17 | huberman.rile.yt | gone |
| 2022-01-04 | qr-code.ai | gone |
| 2022-05-03 | mypath.ai | gone |
| 2012-06-01 | YCThread Thread makes it incredibly easy to dress well, using stylists and AI · thread.com | gone |
| 2022-09-21 | phantasmagoria.stavros.io | gone |
| 2023-05-12 | logicloop.com | gone |
| 2023-08-23 | gentrace.ai | gone |
| 2023-03-31 | platoeducation.ai | gone |
| 2023-03-05 | turingjest.app | gone |
| 2023-08-13 | notyet.news | gone |
| 2023-08-17 | textify.storia.ai | gone |
| 2021-07-30 | volantai.org | gone |
| 2023-11-23 | mycyclopedia.co | gone |
| 2023-11-29 | docu.review | gone |
| 2023-09-18 | gron.games | gone |
| 2023-06-01 | todobot.ai | gone |
| 2021-01-01 | YCAXAR AI Multi-agent orchestration platform · axar.ai | gone |
| 2023-10-06 | whattoreadafter.xyz | gone |
| 2020-01-01 | AI-enabled automation of diagnostic radiology workflow and reporting. · synapsica.com | gone |
| 2023-07-29 | neuralsupport.online | gone |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.