You asked about Machine Learning
140 people built something like it. 0 are gone.
That is 0% of the ones whose fate we could settle, against 23% across the whole register.
| Launched | What it was | Today |
|---|---|---|
| 2016-06-01 | YCScale AI Data-centric infrastructure to accelerate the development of AI · scale.com | still up |
| 2020-06-01 | YCTaktile Transform your decision-making with reliable AI agents in weeks, not… · taktile.com | still up |
| 2021-01-01 | YCEncord The data layer for physical AI · encord.com | still up |
| 2022-01-01 | YCvoize We build the AI companion for nurses, to create time for care. · voize.de | still up |
| 2018-01-01 | PROVEN is using AI, data and personalization to disrupt CPG · provenskincare.com | still up |
| 2022-01-01 | Compliant-Ready AI for the Enterprise · dynamo.ai | still up |
| 2022-01-01 | YCLanceDB Open-source, serverless vectordb for production-scale generative AI · lancedb.com | still up |
| 2024-06-01 | YCFINNY AI The organic growth engine for financial advisors · finny.com | still up |
| 2025-01-01 | YCMundo AI The data layer for perceptual intelligence · mundoai.world | still up |
| 2022-01-01 | YCSpade Spade is the data and AI platform for modern finance. · spade.com | still up |
| 2020-06-01 | Financial data layer for AI-powered finance and accounting · blueonion.ai | still up |
| 2021-06-01 | YCMach9 AI CAD Software for Civil Engineering · mach9.ai | still up |
| 2021-06-01 | The fastest way to ship airtight AI · openlayer.com | still up |
| 2023-01-01 | YC222 the AI social facilitator for offline human to human interactions · 222.place | still up |
| 2016-01-01 | YCRevl AI edited video souvenirs as a service · revl.com | still up |
| 2020-01-01 | YCHandoff AI estimator & agent for remodelers. · handoff.ai | still up |
| 2022-01-01 | LLM for Legal in Brazil · lexter.ai | still up |
| 2023-01-01 | Automating Healthcare Revenue Cycle Management with AI Workforce · combinehealth.ai | still up |
| 2020-06-01 | AI-native Operating System for Enterprise Ecommerce Companies · hypotenuse.ai | still up |
| 2022-06-01 | YCFini Fini | Automate 80% of enterprise support with AI agents · usefini.com | still up |
| 2022-01-01 | Rapid medical data annotation · redbrickai.com | still up |
| 2025-09-01 | Agentic AI for Society Builders · brickanta.com | still up |
| 2024-09-01 | YCArchil The high-performance file system that connects AI to data · archil.com | still up |
| 2020-01-01 | YCAtmo Ultra-precise AI weather forecasting. · atmo.ai | still up |
| 2019-06-01 | Vibe code games. · rosebud.ai | still up |
| 2021-06-01 | Plan and review AI generated code · vibekanban.com | still up |
| 2023-01-01 | YCBoundary The programming language for AI · boundaryml.com | still up |
| 2022-06-01 | YCLamin Open data platform for traceable, multimodal AI · lamin.ai | still up |
| 2023-01-01 | Generative AI for protein design · diffuse.bio | still up |
| 2020-01-01 | YCOda AI Agent for Home Design · odastudio.ai | still up |
| 2024-01-01 | Applied AI Data Research Lab Encoding Human Expertise into Machines… · useocular.com | still up |
| 2023-06-01 | YCGuac AI-powered forecasting & replenishment for grocery · guac.com | still up |
| 2023-06-01 | YCSubsets AI-driven Retention Automation for subscription media businesses. · subsets.com | still up |
| 2025-06-01 | Analyze any footage, without training a model · ondeckai.com | still up |
| 2021-06-01 | AI-designed Affinity Reagents · medium.bio | still up |
| 2025-09-01 | YCAllus AI Transforming manufacturing with our next-gen Vision Foundation Model · allus.ai | still up |
| 2026-06-01 | Network for Physical AI Data Business · deepreach.ai | still up |
| 2024-06-01 | YCAnglera AI-Powered Product Data Enrichment · anglera.com | still up |
| 2025-01-01 | YCOsmosis Reinforcement Learning (RL) for AI Agents · osmosis.ai | still up |
| 2024-09-01 | YCMetreecs AI-powered demand forecasting for retail · metreecs.com | still up |
| 2023-01-01 | Developing long-lasting drug formulations 50% faster · persist-ai.com | still up |
| 2022-01-01 | YCStarling AI enabling digital urine diagnostics in the home · starlingmedical.com | still up |
| 2018-01-01 | iPhone-based driver monitoring for commercial fleets. · observantai.com | still up |
| 2022-01-01 | YCToko AI English Tutor · tokotutor.com | still up |
| 2025-01-01 | YCNitrode Frontier AI research to advance game development · nitrode.com | still up |
| 2021-06-01 | Computer vision that makes the industrial workplace, safer · protex.ai | still up |
| 2023-06-01 | Don't die of heart disease. Empirical is the first AI-native heart… · empirical.health | still up |
| 2025-06-01 | Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF. · roboticscenter.ai | still up |
| 2023-01-01 | Dataset Management for AI Trainers · truthsuite.com | still up |
| 2025-06-01 | AI powered brokerage reducing residential rental commissions in NYC… · spotlight.realty | still up |
| 2024-06-01 | The video context layer for AI. · cloudglue.dev | still up |
| 2024-06-01 | AI that operates quantum computers for scientific discovery · conductorquantum.com | still up |
| 2022-01-01 | Serverless Infrastructure Platform for AI · cerebrium.ai | still up |
| 2026-06-01 | YCPRINCEPS AI-native insurance company for the compute economy · princeps.dev | still up |
| 2026-09-01 | Discover novel defense related materials/molecules. · chempilot.ai | still up |
| 2023-06-01 | YCPropRise The AI platform for CRE investment teams · proprise.ai | still up |
| 2026-09-01 | YCTrueMile An AI-operated logistics company. · truemile.ai | still up |
| 2022-06-01 | YCTypeLess AI messaging API for smarter, faster communication. · apps.apple.com | still up |
| 2019-01-01 | Language models for enterprise applications. · sapling.ai | still up |
| 2024-06-01 | YCSimplex AI agents to enroll providers with payors · simplex.sh | still up |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.