You asked about Industrial Bio
100 people built something like it. 0 are gone.
That is 0% of the ones whose fate we could settle, against 23% across the whole register.
| Launched | What it was | Today |
|---|---|---|
| 2023-01-01 | Gen-AI Designed Enzymes for Pharmaceutical Innovation · pando.bio | still up |
| 2025-06-01 | AI infrastructure for biosecurity · twentytwo.bio | still up |
| 2021-01-01 | YCTractian Physical AI for asset-heavy industries · tractian.com | still up |
| 2016-01-01 | AI + Robotics for the Built World · geckorobotics.com | still up |
| 2026-01-01 | Physical AI data lab · humanarchive.ai | still up |
| 2022-06-01 | YCCambio AI-native commercial real estate operations · cambio.ai | still up |
| 2021-01-01 | Physical AI for Warehouses and Factories · fluxauto.ai | still up |
| 2022-06-01 | YCPaces Agentic AI for Power Projects and AI Infrastructure · paces.com | still up |
| 2019-01-01 | YCOverview Reshaping industrial quality with AI, hardware, and software · overview.ai | still up |
| 2018-01-01 | Orangewood Labs makes worlds most affordable and easiest AI robot arms · orangewood.co | still up |
| 2026-06-01 | Mass-produced AI strike systems and Counter-UAS · isengardindustries.com | still up |
| 2022-01-01 | YCKorrAI Traceable AI for billion-dollar infrastructure. · korrai.com | still up |
| 2020-06-01 | AI-native Robotics · nexterarobotics.com | still up |
| 2019-06-01 | Arpeggio Bio develops drugs targeting transcription factors using AI… · arpeggiobio.com | still up |
| 2024-01-01 | AI Inference Platform for Drug Discovery · tamarind.bio | still up |
| 2021-06-01 | YCFerveret Nuclear-inspired cooling that turns wasted power into more AI compute · ferveret.com | still up |
| 2022-06-01 | YCCerrion Video AI to automatically detect and respond to production line… · cerrion.com | still up |
| 2025-01-01 | YCConntour AI to monitor thousands of security cameras. · conntour.com | still up |
| 2025-01-01 | AI powered operating system for distributors and OEMs · salespatriot.com | still up |
| 2025-01-01 | YCBindwell Discovering new pesticides with AI · bindwell.ai | still up |
| 2019-06-01 | YCEARTH AI Predictive Explorer and Driller for Critical Metal Deposits · earth-ai.com | still up |
| 2024-06-01 | YCDistro The AI co-pilot for sales reps at industrial wholesale distributors. · distro.app | still up |
| 2022-06-01 | YCLamin Open data platform for traceable, multimodal AI · lamin.ai | still up |
| 2020-01-01 | YCAtmo Ultra-precise AI weather forecasting. · atmo.ai | still up |
| 2025-09-01 | YCMOVEdot AI Agents for Hardware Engineering · movedot.ai | still up |
| 2023-01-01 | Generative AI for protein design · diffuse.bio | still up |
| 2022-01-01 | IndustrialNext builds the AI brain for manufacturing –… · industrialnext.ai | still up |
| 2022-01-29 | typing.ai | still up |
| 2025-01-01 | AI drug discovery platform for neurotherapeutics · exintherapeutics.com | still up |
| 2020-06-01 | We use AI to design antibodies for intractable diseases · nabla.bio | still up |
| 2021-01-01 | YCBiodock Cloud AI microscopy automation · biodock.ai | still up |
| 2024-01-01 | Agent-Driven Engineering · navier.ai | still up |
| 2026-01-01 | Modular AI-Commanded Drones for Defence · seeing-systems.com | still up |
| 2025-06-01 | AI models that teach robots new skills in hours · vernerobotics.com | still up |
| 2023-06-01 | YCNectar Manage energy cost & usage with AI for facility & sustainability teams · nectarclimate.com | still up |
| 2024-01-01 | AI for Robot Arms in Factories · pivotrobotics.com | still up |
| 2026-09-01 | Robotics for AI Infrastructure · lambdarobotics.ai | still up |
| 2021-06-01 | AI-designed Affinity Reagents · medium.bio | still up |
| 2025-09-01 | YCAllus AI Transforming manufacturing with our next-gen Vision Foundation Model · allus.ai | still up |
| 2025-06-01 | Build AI agents for field technicians to diagnose and sell 10x better · noso.so | still up |
| 2023-06-01 | YCNanograb Deliver genes to any cell with AI · nanograb.com | still up |
| 2025-06-01 | YCAvent AI agents for industrial commerce · aventindustrial.com | still up |
| 2026-01-01 | The AI-native platform for next-generation protein characterization. · 10xscience.com | still up |
| 2026-06-01 | YCMarengo AI-Native Engineering Firm designing Data Centers · marengox.com | still up |
| 2020-01-01 | AI that tells mining companies where to mine to maximize profits · stratum.ai | still up |
| 2021-06-01 | Computer vision that makes the industrial workplace, safer · protex.ai | still up |
| 2025-06-01 | YCNovaflow The AI data analyst for biology labs · novaflow.ai | still up |
| 2024-06-01 | Gen AI molecular simulations that reproduce wetlab results · angstrom-ai.com | still up |
| 2025-06-01 | Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF. · roboticscenter.ai | still up |
| 2024-06-01 | AI that operates quantum computers for scientific discovery · conductorquantum.com | still up |
| 2026-06-01 | AI-native electronics manufacturing for the American industrial base · provenmetal.com | still up |
| 2026-01-01 | AI benchmarks that measure general intelligence and inspire new ideas · arcprize.org | still up |
| 2025-06-01 | YCConvexia The world's first AI-maximalist pharma company · convexia.bio | still up |
| 2026-06-01 | AI that turns any camera to an autonomous worker with real-time vision · openvector.com | still up |
| 2026-06-01 | YC6thSense Nervous System for Physical AI · 6thsense.dev | still up |
| 2026-06-01 | YCWonderTx Extrapolative AI to unlock First-in-Class drugs · wondertx.ai | still up |
| 2024-09-01 | AI for life sciences documents · raycaster.ai | still up |
| 2024-06-01 | YCAluna Data for biomedical AI · alunadata.com | still up |
| 2024-06-01 | The AI scientist for always-on biodefense · aminoanalytica.com | still up |
| 2026-09-01 | AI spacecraft operators that lives onboard the vehicle · orcaaerospace.com | still up |
How this compares
Y Combinator reports its own outcomes, including acquisitions. The other two are judged by asking the domain, so they are not measured the same way and are never averaged together.
Older launches have had longer to die, so this slope is expected. A year that broke it would mean something is wrong with the checking.
The register re-probes every domain it holds. Some that answered last month stop answering. We send that list — what went quiet, and what it was — once a month. Nothing else.
How this was made. Show HN entries are every post from 2021 to 2023 with at least five points that linked to its own domain; code hosts and free hosting are excluded, because a repository outlives the effort behind it. Product Hunt entries needed 100 votes — a far higher bar, so they are the promoted top slice rather than a like-for-like sample. Both are judged by asking the domain whether it still answers: gone means it no longer resolves, refuses the connection, serves a parking page, or says plainly that it shut down. An HTTP error is not counted as gone — a server answering 404 is one somebody still pays for, and an audit of 25 gone-calls found two such sites alive with only a moved homepage. Y Combinator entries use the status YC publishes itself, which is why only those can say acquired. Squatted domains — a lapsed name now serving somebody else's site — are not detected, so these figures run slightly low.